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OBJECTIVE: To investigate the effects of resistance exercise on nasal and eye symptoms, quality of life, and levels of inflammatory markers in patients with allergic rhinitis. STUDY DESIGN: A prospective randomized controlled trial. SETTING: Conducted at a single tertiary care center. METHODS: A total of 156 patients with allergic rhinitis were randomly divided into a resistance exercise group and a control group for a 6-month intervention. Changes in nasal symptom scores, eye symptom scores, quality of life scores, and serum IL-4, IL-6, and IgE levels were evaluated. RESULTS: The resistance exercise group showed significantly greater improvement in nasal and eye symptoms, quality of life, and reduction in inflammatory markers compared to the control group (P < 0.05). CONCLUSION: Resistance exercise significantly improved symptoms and quality of life in patients with allergic rhinitis, showing promising clinical potential as an important adjunctive treatment.