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Abbreviations 3f'PCC 3 -factor prothrombin complex concentrate anti-MPO anti myeloperoxidase 4f PCC 4 factor prothrombin complex concentrate anti NMDA anti N methyl-D-aspartate 5 ASA 5-aminosalicylate anti RNP antiribonucleoprotein 5FU 5-fluorouracil anti Sm anti Smith 5 HIAA 5 - hydroxyindoleacetic acid anti TNF anti-tumor necrosis factor 5 HT3 5-hydroxytryptamine-3 AOSD adult onset Still disease 6_MP 6-mercaptopurine APLAS antiphospholipid antibody syndrome A-a alveolar-arterial oxygen gradient aPTT activated partial thromboplastin time AA amyloid A AR aortic regurgitation; absolute risk AAA abdominal aortic aneurysm ARB angiotensin receptor blocker AAT 0r antitrypsin ARDS acute respiratory distress syndrome ABG arterial blood gas ARI absolute risk increase ABI ankle-brachial index ARR absolute risk reduction ABIM American Board of Internal Medicine ART antiretroviral therapy ABPM ambulatory blood pressure monitoring AS aortic stenosis ABVD doxorubicin (Adriamycin), bleomycin, ASCVD atherosclerotic cardiovascular disease vinblastine. dacarbazine ASD atrial septal def'ect ACC American College of Cardiologr ASH alcoholic steatohepatitis ACE angiotensin converting enzyme AST aspa rtate aminotransferase ACL anterior cruciate ligament ATN acute tubular necrosis ACP American College ol Physicians ATRA all frons retinoic acid ACS acute coronary syndrome ATS American Thoracic Society ACTH adrenocorticotropic hormone AUDIT C Alcohol Use Disorders Identification Test ADA American Diabetes Association AV atrioventricular ADH antidiuretic hormone AVM arteriovenous malformation ADHD attention-defi cit /hyperactivity disorder AVNRT atrioventricular nodal reentrant tachycardia ADPKD autosomal dominant polycystic kidney disease AVP arginine vasopressin ADT androgen deprivation therapy AVRT atrioventricular reciprocating tachycardia AED antiepileptic drug B hcc beta human chorionic gonadotropin AF atrial fibrillation Pr-GPI beta-2 glycoprotein I AFLP acute fatty liver of pregnancy BCC basal cell carcinoma AFP s-fetoprotein BE Barrett esophagus AGEP acute generalized exanthematous pustulosis BID twice daily AH alcoholic hepatitis BMI body mass index AHA American Heart Association BNP ts type natriuretic peptide AHI apnea hypopneaindex BP blood pressure AHR abacavir hypersensitivity reaction BPAP bilevel positive airway pressure AIDS acquired immunodeliciency syndrome BPH benign prostatic hyperplasia AIN acute interstitial nephritis BPPV benign paroxysmal positional vertigo AIP autoimmune pancreatitis BRCA breast cancer susceptibility gene AKI acute kidney injury BUN blood urea nitrogen AL amyloidosis immunoglobulin light chain amyloidosis CABG coronary artery bypass graft ALL acute lymphoblastic leukemia CAD coronary artery disease ALS amyotrophic lateral sclerosis CA MRSA community acquired methicillin-resistant ALT alanine aminotransferase Staphylococcus oureus AMD age-related macular degeneration CAN contrast associated nephropathy AMH asymptomatic microscopic hematuria c-ANCA cltoplasmic antineutrophil cytoplasmic antibody AMI acute mesenteric ischemia CAP communify-acquired pneumonia AML acute myeloid leukemia CAPOX capecitabine plus oxaliplatin AMS acute mountain sickness CAUTI catheter associated urinary tract infection ANA antinuclear antibody CBC complete blood count ANCA antineutrophil cytoplasmic antibody CBT cognitive behavioral therapy anti-CCP anti cyclic citrullinated peptide CCB calcium channel blocker anti dsDNA anti-double stranded DNA CDS clinical decision support anti-HBc antibodies to hepatitis B core antigen CEA carcinoembryonic antigen anti-HBe antibodies to hepatitis B e antigen CER control event rate anti-HBs antibodies to hepatitis B surface antigen CF cystic tibrosis

3f'PCC 3 -factor prothrombin complex concentrate anti-MPO anti myeloperoxidase 4f PCC 4 factor prothrombin complex concentrate anti NMDA anti N methyl-D-aspartate 5 ASA 5-aminosalicylate anti RNP antiribonucleoprotein 5FU 5-fluorouracil anti Sm anti Smith 5 HIAA 5 - hydroxyindoleacetic acid anti TNF anti-tumor necrosis factor 5 HT3 5-hydroxytryptamine-3 AOSD adult onset Still disease 6_MP 6-mercaptopurine APLAS antiphospholipid antibody syndrome A-a alveolar-arterial oxygen gradient aPTT activated partial thromboplastin time AA amyloid A AR aortic regurgitation; absolute risk AAA abdominal aortic aneurysm ARB angiotensin receptor blocker AAT 0r antitrypsin ARDS acute respiratory distress syndrome ABG arterial blood gas ARI absolute risk increase ABI ankle-brachial index ARR absolute risk reduction ABIM American Board of Internal Medicine ART antiretroviral therapy ABPM ambulatory blood pressure monitoring AS aortic stenosis ABVD doxorubicin (Adriamycin), bleomycin, ASCVD atherosclerotic cardiovascular disease vinblastine. dacarbazine ASD atrial septal def'ect ACC American College of Cardiologr ASH alcoholic steatohepatitis ACE angiotensin converting enzyme AST aspa rtate aminotransferase ACL anterior cruciate ligament ATN acute tubular necrosis ACP American College ol Physicians ATRA all frons retinoic acid ACS acute coronary syndrome ATS American Thoracic Society ACTH adrenocorticotropic hormone AUDIT C Alcohol Use Disorders Identification Test ADA American Diabetes Association AV atrioventricular ADH antidiuretic hormone AVM arteriovenous malformation ADHD attention-defi cit /hyperactivity disorder AVNRT atrioventricular nodal reentrant tachycardia ADPKD autosomal dominant polycystic kidney disease AVP arginine vasopressin ADT androgen deprivation therapy AVRT atrioventricular reciprocating tachycardia AED antiepileptic drug B hcc beta human chorionic gonadotropin AF atrial fibrillation Pr-GPI beta-2 glycoprotein I AFLP acute fatty liver of pregnancy BCC basal cell carcinoma AFP s-fetoprotein BE Barrett esophagus AGEP acute generalized exanthematous pustulosis BID twice daily AH alcoholic hepatitis BMI body mass index AHA American Heart Association BNP ts type natriuretic peptide AHI apnea hypopneaindex BP blood pressure AHR abacavir hypersensitivity reaction BPAP bilevel positive airway pressure AIDS acquired immunodeliciency syndrome BPH benign prostatic hyperplasia AIN acute interstitial nephritis BPPV benign paroxysmal positional vertigo AIP autoimmune pancreatitis BRCA breast cancer susceptibility gene AKI acute kidney injury BUN blood urea nitrogen AL amyloidosis immunoglobulin light chain amyloidosis CABG coronary artery bypass graft ALL acute lymphoblastic leukemia CAD coronary artery disease ALS amyotrophic lateral sclerosis CA MRSA community acquired methicillin-resistant ALT alanine aminotransferase Staphylococcus oureus AMD age-related macular degeneration CAN contrast associated nephropathy AMH asymptomatic microscopic hematuria c-ANCA cltoplasmic antineutrophil cytoplasmic antibody AMI acute mesenteric ischemia CAP communify-acquired pneumonia AML acute myeloid leukemia CAPOX capecitabine plus oxaliplatin AMS acute mountain sickness CAUTI catheter associated urinary tract infection ANA antinuclear antibody CBC complete blood count ANCA antineutrophil cytoplasmic antibody CBT cognitive behavioral therapy anti-CCP anti cyclic citrullinated peptide CCB calcium channel blocker anti dsDNA anti-double stranded DNA CDS clinical decision support anti-HBc antibodies to hepatitis B core antigen CEA carcinoembryonic antigen anti-HBe antibodies to hepatitis B e antigen CER control event rate anti-HBs antibodies to hepatitis B surface antigen CF cystic tibrosis 393

Abbreviations CFU colony-forming unit EE eosinophilic esophagitis CHro total hemolytic complement EEG electroencephalogram CI confidence interval EER experimental event rate CIWA AT Clinical Institute Withdrawal Assessment for EF ejection fraction Alcohol. Revised EGD esophagogastroduodenoscopy CK creatine kinase EGFR epidermal growth factor receptor CKD chronic kidney disease eGFR estimated glomerular filtration rate CLL chronic lymphocytic leukemia EHEC enterohemorrhagic Escherichio coli CML chronic myeloid Ieukemia EHR electronic health record CMR cardiac magnetic resonance (imaging) EIA enzyme immunoassay CMV cytomegalovirus ELISA enzyme linked immunosorbent assay CNS central nervous system EM e44hema multiforme COPD chronic obstructive pulmonary disease EMG electromyography cox 2 cyclooxygenase 2 EN erythema nodosum CPAP continuous positive airway pressure ENT ear, nose, and throat CPOE computerized physician order entry ER estrogen receptor CPP calcium pyrophosphate ERCP endoscopic retrograde cholangiopancreatography CPPD calcium pyrophosphate deposition ESBL extended spectmm B lactamase CRAO central retinal arterial occlusion ESKD end stage kidney disease CRC colorectal cancer ESR erythrocyte sedimentation rate CRE carbapenem resistant Enterobacteriaceae ETEC enterotoxi genic Escherlc hia coli CRP C reactive protein FADIR Flexion, ADduction, and Internal Rotation CRVO central retinal vein occlusion FDR first-degree relative CSF cerebrospinal fluid FEn, fiactional excretion of sodium CT computed tomography FEro* fractional excretion of filtered phosphate CTA computed tomography angiography FEu.." tiactional excretion of urea CTEPH chronic thromboembolic pulmonary FEVr forced expiratory volume exhaled in 1 second hypertension FFP fresh frozen plasma CTP Child Turcotte-Pugh FIT fecal immunochemical test CUP carcinoma of unknown primary I.'MF familial Mediterranean fever CV cardiovascular FNAB fine needle aspiration biopsy CVA cerebrovascular accident FOBT fecal occult blood testing CVD cardiovascular disease FODMAPS fermentable oligosaccharides, disaccharides, CVID common variable immunodefi ciency monosaccharides, and polyols CVP central venous pressure FOLFIRI 5 fluorouracil, leucovorin, and irinotecan DASH Dietary Approaches to Stop Hypertension FOLFIRINOX S fluorouracil, leucovorin, irinotecan, and DAT direct antiglobulin test oxaliplatin DBP diastolic blood pressure FOLFOX 5-fluorouracil, leucovorin, and oxaliplatin DCIS ductal carcinoma in situ FRAX Fracture Risk Assessment Tool DDAVP l-dermino-S D arginine vasopressin FSH follicle stimulating hormone DEXA dual enerry x ray absorptiometry FTA ABS fluorescent treponemal antibody absorption test DHEAS dehydroepiandrosterone sulfate FVC forced vital capacity DHSS Department of Health and Human Services G6PD glucose 6 phosphate dehydrogenase DI diabetes insipidus GAD65 glutamate decarboxylase antibody DIC disseminated intravascular coagulation GBM glomerular basement membrane DIP distal interphalangeal GDH glutamate dehydrogenase DISH diffuse idiopathic skeletal hyperostosis GE gastroesophageal DKA diabetic ketoacidosis GERD gastroesophageal refl ux disease DLCL diftuse large cell lymphoma GFR glomerular filtration rate Dlcrr diffusing capacity of lung for carbon monoxide GH growth hormone DMARD disease modifying antirheumatic drug GI gastrointestinal dMMR defective mismatch repair GN glomerulonephritis DNA deoxyribonucleic acid GnRH gonadotropin-releasing hormone DOAC direct oral anticoagulant CP glycoprotein DPLD difluse parenchymal lung disease GU genitourinary DRESS drug reaction with eosinophilia and systemic GVHD graft versus host disease symptoms Hr histamine type 1 dsDNA double stranded DNA H2 histamine type 2 DVT deep venous thrombosis HACE high-altitude cerebral edema EA early antigen HAI high altitude illness EBNA I Epstein Barr nuclear antigen 1 HAP hospital acquired pneumonia EBV Epstein Barr virus HAPB high altitude periodic breathing ECG electrocardiogram HAPE high altitude pulmonary edema ED erectile dysfunction HAV hepatitis A virus EDTA ethylenediaminetetraacetic acid HBeAg hepatitis B e antigen

CFU colony-forming unit EE eosinophilic esophagitis CHro total hemolytic complement EEG electroencephalogram CI confidence interval EER experimental event rate CIWA AT Clinical Institute Withdrawal Assessment for EF ejection fraction Alcohol. Revised EGD esophagogastroduodenoscopy CK creatine kinase EGFR epidermal growth factor receptor CKD chronic kidney disease eGFR estimated glomerular filtration rate CLL chronic lymphocytic leukemia EHEC enterohemorrhagic Escherichio coli CML chronic myeloid Ieukemia EHR electronic health record CMR cardiac magnetic resonance (imaging) EIA enzyme immunoassay CMV cytomegalovirus ELISA enzyme linked immunosorbent assay CNS central nervous system EM e44hema multiforme COPD chronic obstructive pulmonary disease EMG electromyography cox 2 cyclooxygenase 2 EN erythema nodosum CPAP continuous positive airway pressure ENT ear, nose, and throat CPOE computerized physician order entry ER estrogen receptor CPP calcium pyrophosphate ERCP endoscopic retrograde cholangiopancreatography CPPD calcium pyrophosphate deposition ESBL extended spectmm B lactamase CRAO central retinal arterial occlusion ESKD end stage kidney disease CRC colorectal cancer ESR erythrocyte sedimentation rate CRE carbapenem resistant Enterobacteriaceae ETEC enterotoxi genic Escherlc hia coli CRP C reactive protein FADIR Flexion, ADduction, and Internal Rotation CRVO central retinal vein occlusion FDR first-degree relative CSF cerebrospinal fluid FEn, fiactional excretion of sodium CT computed tomography FEro* fractional excretion of filtered phosphate CTA computed tomography angiography FEu.." tiactional excretion of urea CTEPH chronic thromboembolic pulmonary FEVr forced expiratory volume exhaled in 1 second hypertension FFP fresh frozen plasma CTP Child Turcotte-Pugh FIT fecal immunochemical test CUP carcinoma of unknown primary I.'MF familial Mediterranean fever CV cardiovascular FNAB fine needle aspiration biopsy CVA cerebrovascular accident FOBT fecal occult blood testing CVD cardiovascular disease FODMAPS fermentable oligosaccharides, disaccharides, CVID common variable immunodefi ciency monosaccharides, and polyols CVP central venous pressure FOLFIRI 5 fluorouracil, leucovorin, and irinotecan DASH Dietary Approaches to Stop Hypertension FOLFIRINOX S fluorouracil, leucovorin, irinotecan, and DAT direct antiglobulin test oxaliplatin DBP diastolic blood pressure FOLFOX 5-fluorouracil, leucovorin, and oxaliplatin DCIS ductal carcinoma in situ FRAX Fracture Risk Assessment Tool DDAVP l-dermino-S D arginine vasopressin FSH follicle stimulating hormone DEXA dual enerry x ray absorptiometry FTA ABS fluorescent treponemal antibody absorption test DHEAS dehydroepiandrosterone sulfate FVC forced vital capacity DHSS Department of Health and Human Services G6PD glucose 6 phosphate dehydrogenase DI diabetes insipidus GAD65 glutamate decarboxylase antibody DIC disseminated intravascular coagulation GBM glomerular basement membrane DIP distal interphalangeal GDH glutamate dehydrogenase DISH diffuse idiopathic skeletal hyperostosis GE gastroesophageal DKA diabetic ketoacidosis GERD gastroesophageal refl ux disease DLCL diftuse large cell lymphoma GFR glomerular filtration rate Dlcrr diffusing capacity of lung for carbon monoxide GH growth hormone DMARD disease modifying antirheumatic drug GI gastrointestinal dMMR defective mismatch repair GN glomerulonephritis DNA deoxyribonucleic acid GnRH gonadotropin-releasing hormone DOAC direct oral anticoagulant CP glycoprotein DPLD difluse parenchymal lung disease GU genitourinary DRESS drug reaction with eosinophilia and systemic GVHD graft versus host disease symptoms Hr histamine type 1 dsDNA double stranded DNA H2 histamine type 2 DVT deep venous thrombosis HACE high-altitude cerebral edema EA early antigen HAI high altitude illness EBNA I Epstein Barr nuclear antigen 1 HAP hospital acquired pneumonia EBV Epstein Barr virus HAPB high altitude periodic breathing ECG electrocardiogram HAPE high altitude pulmonary edema ED erectile dysfunction HAV hepatitis A virus EDTA ethylenediaminetetraacetic acid HBeAg hepatitis B e antigen 394

Abbreviations HBIG hepatitis B immune globulin LAMA long-acting muscarinic agent (also called long HBPM home blood pressure measurement acting anticholinergic agent) HBsAg hepatitis B surface antigen LBBB left bundle branch block HBV hepatitis B virus LDH lactate dehydrogenase hCG human chorionic gonadotropin LDL Iow density lipoprotein HCC hepatocellular carcinoma LES lower esophageal sphincter HCM hypertrophic cardiomyopathy LFT liver function test HCP health care personnel LGI lower gastrointestinal HCV hepatitis C virus LH luteinizing hormone HELLP hemolysis, elevated liver enzyme levels, and a low LKM liver-kidney microsome platelet count LLN lower limit of normal HES hypereosinophilic syndromes LLQ left lower quadrant HF heart failure LMWH low-molecular weight heparin HFpEF heart failure with preserved ejection fraction LN lupus nephritis HFTEF heart failure with reduced ejection fraction LP lumbar puncture HGA human granculocytic anaplasmosis LR likelihood ratio HHS hyperglycemic hyperosmolar syndrome LIBI latent tuberculosis infection HIDA hepatobiliary iminodiacetic acid LV left ventricular HINTS head impulse, nystagmus, and test of skew LVAD left ventricular assist device HIPAA Health Insurance Portability and Accountability LVEF left ventricular ejection fraction Act LVH left ventricular hypertrophy HIT heparin-induced thrombocytopenia LVOT left ventricular outflow tract HITT heparin-induced thrombocytopenia with MAC My cob actertum ou iu m complex thrombosis MACE major adverse cardiac event HIV human immunodefi cienry virus MAOI monoamine oxidase inhibitor HLA human leukocye antigens MALT mucosa associated lymphoid tissue HME human monocytic ehrlichiosis MAP mean arterial pressure HNPCC hereditary nonpolyposis colorectal cancer MAT multifocal atrial tachycardia HPA human platelet antigen MCL medial collateral ligament HPV human papillomavirus MCP metacarpophalangeal HR hazard ratio; heart rate MCTD mixed connective tissue disease HRCT high-resolution computed tomography MCV mean corpuscular volume HSCT hematopoietic stem cell transpi:rntation MDF Maddrey Discriminant Function HSE herpes simplex encephalitis MDRD Modification of Diet in Renal Disease HSV herpes simplex virus MDS myelodysplastic syndromes HUS hemolytic uremic syndrome MELD Model for End-Stage Liver Disease lA-2 islet antigen-2 antibody MENl multiple endocrine neoplasia type 1 IBD inflammatory bowel disease MEN2 multiple endocrine neoplasia tlpe 2 IBS irritable bowel syndrome METs metabolic equivalents IBS_C irritable bowel syndrome with constipation MG myasthenia gravis IBS D irritable bowel syndrome with diarrhea MGUS monoclonal gammopathy of undetermined IBS M mixed irritable bowel syndrome significance ICD implantable cardioverter defibrillator MHA TP microhemagglutination assay for Treponema ICH intracerebral hemorrhage pallidum ICU intensive care unit MI myocardial infarction IDSA Infectious Disease Society of America MIBG metaiodobenzylguanidine IE infective endocarditis MMR measles, mumps, rubella IGF-1 insulin-like growth factor-1 MPA microscopic polyangiitis lgM anti-HAV IgM antibodies to hepatitis A virus MPGN membranoproliferative glomerulonephritis IGRA interferon-1 release assay MPN myeloproliferative neoplasm IM intramuscular MPO myeloperoxidase INR intemational normalized ratio MR mitral regurgitation IPF idiopathic pulmonary librosis MRA magnetic resonance angiography IPSS-R revised International Prognostic Scoring System MRCP magnetic resonance cholangiopancreatography IRIS immune reconstitution infl ammatory syndrome MRI magnetic resonance imaging ITP immune thrombocytopenic purpura MRSA methicillin resistant Staphylococcus oureus IV intravenous MS multiple sclerosis IVIG intravenous immune globulin MSSA methicillin-sensitive StophUIo coccus oureus IVC inferior vena cava mTOR mammalian target of rapamycin JNC 8 Eighth Joint National Committee MTP metatarsophalangeal JVD jugular venous distention MVP mitral valve prolapse KOH potassium hydroxide N/A not applicable LABA long-acting p2-agonist NAAT nucleic acid amplification testing LAC lupus anticoagulant NAFLD nonalcoholic fatty liver disease I,AM Iymphangioleiomyomatosis NASH nonalcoholic steatohepatitis

HBIG hepatitis B immune globulin LAMA long-acting muscarinic agent (also called long HBPM home blood pressure measurement acting anticholinergic agent) HBsAg hepatitis B surface antigen LBBB left bundle branch block HBV hepatitis B virus LDH lactate dehydrogenase hCG human chorionic gonadotropin LDL Iow density lipoprotein HCC hepatocellular carcinoma LES lower esophageal sphincter HCM hypertrophic cardiomyopathy LFT liver function test HCP health care personnel LGI lower gastrointestinal HCV hepatitis C virus LH luteinizing hormone HELLP hemolysis, elevated liver enzyme levels, and a low LKM liver-kidney microsome platelet count LLN lower limit of normal HES hypereosinophilic syndromes LLQ left lower quadrant HF heart failure LMWH low-molecular weight heparin HFpEF heart failure with preserved ejection fraction LN lupus nephritis HFTEF heart failure with reduced ejection fraction LP lumbar puncture HGA human granculocytic anaplasmosis LR likelihood ratio HHS hyperglycemic hyperosmolar syndrome LIBI latent tuberculosis infection HIDA hepatobiliary iminodiacetic acid LV left ventricular HINTS head impulse, nystagmus, and test of skew LVAD left ventricular assist device HIPAA Health Insurance Portability and Accountability LVEF left ventricular ejection fraction Act LVH left ventricular hypertrophy HIT heparin-induced thrombocytopenia LVOT left ventricular outflow tract HITT heparin-induced thrombocytopenia with MAC My cob actertum ou iu m complex thrombosis MACE major adverse cardiac event HIV human immunodefi cienry virus MAOI monoamine oxidase inhibitor HLA human leukocye antigens MALT mucosa associated lymphoid tissue HME human monocytic ehrlichiosis MAP mean arterial pressure HNPCC hereditary nonpolyposis colorectal cancer MAT multifocal atrial tachycardia HPA human platelet antigen MCL medial collateral ligament HPV human papillomavirus MCP metacarpophalangeal HR hazard ratio; heart rate MCTD mixed connective tissue disease HRCT high-resolution computed tomography MCV mean corpuscular volume HSCT hematopoietic stem cell transpi:rntation MDF Maddrey Discriminant Function HSE herpes simplex encephalitis MDRD Modification of Diet in Renal Disease HSV herpes simplex virus MDS myelodysplastic syndromes HUS hemolytic uremic syndrome MELD Model for End-Stage Liver Disease lA-2 islet antigen-2 antibody MENl multiple endocrine neoplasia type 1 IBD inflammatory bowel disease MEN2 multiple endocrine neoplasia tlpe 2 IBS irritable bowel syndrome METs metabolic equivalents IBS_C irritable bowel syndrome with constipation MG myasthenia gravis IBS D irritable bowel syndrome with diarrhea MGUS monoclonal gammopathy of undetermined IBS M mixed irritable bowel syndrome significance ICD implantable cardioverter defibrillator MHA TP microhemagglutination assay for Treponema ICH intracerebral hemorrhage pallidum ICU intensive care unit MI myocardial infarction IDSA Infectious Disease Society of America MIBG metaiodobenzylguanidine IE infective endocarditis MMR measles, mumps, rubella IGF-1 insulin-like growth factor-1 MPA microscopic polyangiitis lgM anti-HAV IgM antibodies to hepatitis A virus MPGN membranoproliferative glomerulonephritis IGRA interferon-1 release assay MPN myeloproliferative neoplasm IM intramuscular MPO myeloperoxidase INR intemational normalized ratio MR mitral regurgitation IPF idiopathic pulmonary librosis MRA magnetic resonance angiography IPSS-R revised International Prognostic Scoring System MRCP magnetic resonance cholangiopancreatography IRIS immune reconstitution infl ammatory syndrome MRI magnetic resonance imaging ITP immune thrombocytopenic purpura MRSA methicillin resistant Staphylococcus oureus IV intravenous MS multiple sclerosis IVIG intravenous immune globulin MSSA methicillin-sensitive StophUIo coccus oureus IVC inferior vena cava mTOR mammalian target of rapamycin JNC 8 Eighth Joint National Committee MTP metatarsophalangeal JVD jugular venous distention MVP mitral valve prolapse KOH potassium hydroxide N/A not applicable LABA long-acting p2-agonist NAAT nucleic acid amplification testing LAC lupus anticoagulant NAFLD nonalcoholic fatty liver disease I,AM Iymphangioleiomyomatosis NASH nonalcoholic steatohepatitis 395

Abbreviations NCCN National Comprehensive Cancer Netlvork RAS renin-angiotensin blockade NET neuroendocrine tumor RAST radioallergosorbent test NMO neuromyelitis optica RBBB right bundle branch block NNH number needed to harm RBC red blood cell NN'T number needed to treat R CHOP rituximab, cyclophosphamide, doxorubicin, NPH intermediate-acting insulin or Lente vincristine, prednisolone NPPV noninvasive positive-pressure ventilation RCT randomized controlled trial NPT nonpharmacologic therapy REM rapid eye movement NSAIDS nonsteroidal anti-infl ammatory drugs RF rheumatic fever NSCLC non-small cell lung cancer rfVIla recombinant factor V[[a NSTE ACS non ST elevation acute coronary syndrome RLQ right lower quadrant NSTEMI non ST elevation myocardial infarction RNA ribonucleic acid NYHA New York Heart Association RNP ribonucleoprotein OA osteoarthritis RPGN rapidly progressive glomerulonephritis OGTT oral glucose tolerance test RPR rapid plasma reagin OSA obstructive sleep apnea RR relative risk PAD peripheral arterial disease RRR relative risk reduction PAH pulmonary arterial hypertension RTA renal tubular acidosis p ANCA perinuclear antineutrophil cytoplasmic antibodies rtPA recombinant tissue plasminogen activator PARP poly (ADP ribose) polymerase RUQ right upper quadrant PBC primary biliary cholangitis RV right ventricular PCI percutaneous coronary intervention SAAC serum ascites albumin gradient PCL posterior cruciate ligament SABA short-acting B, agonist PCNSL primary central nervous system lymphoma SAH subarachnoid hemorrhage PCOS polycystic ovary syndrome SAVR surgical aortic valve replacement PCR polymerase chain reaction SBP systolic blood pressure PCV13 13 valent pneumococcal conjugate vaccine SCC squamous cell carcinoma PCWP pulmonary capillary wedge pressure SCLC small cell lung cancer PDI programmed cell death protein 1 SCD sudden cardiac death PDA patent ductus arteriosus SEID systemic exertion intolerance disease PDE 4 phosphodiesterase type 4 SGLI2 sodium- glucose transporter-2 PDE-5 phosphodiesterase type 5 SIADH syndrome of inappropriate antidiuretic hormone PE pulmonary embolism secretion PEEP positive end-expiratory pressure SIBO small intestinal bacterial overgrowth PEF peak expiratory flow SIRS systemic inflammatory response syndrome PEG polyethylene glycol SJS Stevens Johnson syndrome PET positron emission tomography SLE systemic lupus erythematosus PF4 platelet factor 4 SNRI serotonin norepinephrine reuptake inhibitor PFO patent foramen ovale SPEP serum protein electrophoresis PFT pulmonary function test SPN solitary pulmonary nodule PH pulmonary hypertension SSc systemic sclerosis PID pelvic inflammatory disease SSRI selective serotonin reuptake inhibitor PIP proximal interphalangeal STEC Shiga toxin-producing Escherichia coli PMDD premenstrual dysphoric disorder S'TEMI ST elevation myocardial infarction PMN polymorphonuclear STI sexually transmitted inlection PMS premenstmal syndrome SVC superior vena cava PNES psychogen ic nonepi leptic seizures SVT supraventricular tachyca rd ia PNH paroxysmal nocturnal hemoglobinuria T{ free thyroxine PO by mouth TAVI transcatheter aortic valve implantation PPI proton pump inhibitor TB tuberculosis PPSV23 23 valent pneumococcal polysaccharide vaccine TBI traumatic brain injury PR progesterone receptor TBW total body weight PR3 proteinase 3 Tdap diphtheria and reduced tetanus toxoids and PrEP pre exposure prophylaxis acellular pertussis vaccine PSA prostate specific antigen TEE transesophageal echocardiography PSC primary sclerosing cholangitis TEN toxic epidermal necrolysis PSI Pneumonia Severity Index TIA transient ischemic attack PT prothrombin time TIBC total iron binding capacity PTH parathyroid hormone TIMI Thrombolysis in Myocardial lnfarction (risk score) PTSD posttraumatic stress disorder TIPS transjugular intrahepatic portosystemic shunt PUD peptic ulcer disease TLC total lung capacity PV polycythemia vera TNF tumor necrosis factor PVC premature ventricular complex TP EIA Treponema pallidum enzyme immunoassay RA rheumatoid arthritis TPPA Trepone ma pal lidu m particle agglutination RANK receptor activator of nuclear factor kappa B TR tricuspid regurgitation

NCCN National Comprehensive Cancer Netlvork RAS renin-angiotensin blockade NET neuroendocrine tumor RAST radioallergosorbent test NMO neuromyelitis optica RBBB right bundle branch block NNH number needed to harm RBC red blood cell NN'T number needed to treat R CHOP rituximab, cyclophosphamide, doxorubicin, NPH intermediate-acting insulin or Lente vincristine, prednisolone NPPV noninvasive positive-pressure ventilation RCT randomized controlled trial NPT nonpharmacologic therapy REM rapid eye movement NSAIDS nonsteroidal anti-infl ammatory drugs RF rheumatic fever NSCLC non-small cell lung cancer rfVIla recombinant factor V[[a NSTE ACS non ST elevation acute coronary syndrome RLQ right lower quadrant NSTEMI non ST elevation myocardial infarction RNA ribonucleic acid NYHA New York Heart Association RNP ribonucleoprotein OA osteoarthritis RPGN rapidly progressive glomerulonephritis OGTT oral glucose tolerance test RPR rapid plasma reagin OSA obstructive sleep apnea RR relative risk PAD peripheral arterial disease RRR relative risk reduction PAH pulmonary arterial hypertension RTA renal tubular acidosis p ANCA perinuclear antineutrophil cytoplasmic antibodies rtPA recombinant tissue plasminogen activator PARP poly (ADP ribose) polymerase RUQ right upper quadrant PBC primary biliary cholangitis RV right ventricular PCI percutaneous coronary intervention SAAC serum ascites albumin gradient PCL posterior cruciate ligament SABA short-acting B, agonist PCNSL primary central nervous system lymphoma SAH subarachnoid hemorrhage PCOS polycystic ovary syndrome SAVR surgical aortic valve replacement PCR polymerase chain reaction SBP systolic blood pressure PCV13 13 valent pneumococcal conjugate vaccine SCC squamous cell carcinoma PCWP pulmonary capillary wedge pressure SCLC small cell lung cancer PDI programmed cell death protein 1 SCD sudden cardiac death PDA patent ductus arteriosus SEID systemic exertion intolerance disease PDE 4 phosphodiesterase type 4 SGLI2 sodium- glucose transporter-2 PDE-5 phosphodiesterase type 5 SIADH syndrome of inappropriate antidiuretic hormone PE pulmonary embolism secretion PEEP positive end-expiratory pressure SIBO small intestinal bacterial overgrowth PEF peak expiratory flow SIRS systemic inflammatory response syndrome PEG polyethylene glycol SJS Stevens Johnson syndrome PET positron emission tomography SLE systemic lupus erythematosus PF4 platelet factor 4 SNRI serotonin norepinephrine reuptake inhibitor PFO patent foramen ovale SPEP serum protein electrophoresis PFT pulmonary function test SPN solitary pulmonary nodule PH pulmonary hypertension SSc systemic sclerosis PID pelvic inflammatory disease SSRI selective serotonin reuptake inhibitor PIP proximal interphalangeal STEC Shiga toxin-producing Escherichia coli PMDD premenstrual dysphoric disorder S'TEMI ST elevation myocardial infarction PMN polymorphonuclear STI sexually transmitted inlection PMS premenstmal syndrome SVC superior vena cava PNES psychogen ic nonepi leptic seizures SVT supraventricular tachyca rd ia PNH paroxysmal nocturnal hemoglobinuria T{ free thyroxine PO by mouth TAVI transcatheter aortic valve implantation PPI proton pump inhibitor TB tuberculosis PPSV23 23 valent pneumococcal polysaccharide vaccine TBI traumatic brain injury PR progesterone receptor TBW total body weight PR3 proteinase 3 Tdap diphtheria and reduced tetanus toxoids and PrEP pre exposure prophylaxis acellular pertussis vaccine PSA prostate specific antigen TEE transesophageal echocardiography PSC primary sclerosing cholangitis TEN toxic epidermal necrolysis PSI Pneumonia Severity Index TIA transient ischemic attack PT prothrombin time TIBC total iron binding capacity PTH parathyroid hormone TIMI Thrombolysis in Myocardial lnfarction (risk score) PTSD posttraumatic stress disorder TIPS transjugular intrahepatic portosystemic shunt PUD peptic ulcer disease TLC total lung capacity PV polycythemia vera TNF tumor necrosis factor PVC premature ventricular complex TP EIA Treponema pallidum enzyme immunoassay RA rheumatoid arthritis TPPA Trepone ma pal lidu m particle agglutination RANK receptor activator of nuclear factor kappa B TR tricuspid regurgitation 396

i' I Abbreviations i i I TSH th/roid-stimulating hormone VBRT vestibular and balance rehabilitation therapy L TSS toxic shock syndrome VCA vlral capsid antigen i I TST tuberculin skin testing VEGF vascular endothelial growth factor t' TTE tmnsthoracic echocardiography VF ventricular f ibrillation tTG tissue transglutaminase VKA vitamin K antagonist I TTP thrombotic thrombocytopenic purpura v/Q ventilatlon/perfu sion ratio UA urinal,,sis VRE rancomlrcin-resistant enterococci UACS upper airways cough syndrome VSD ventricular septal defect UAG urine anion gap VT ventricular tachycardia UFH unfractionated heparin VTE venous thrcmboembolism UGI upper gastrointestinal vWD von Willebranddisease t ULN upper limit of normal vWF rrcn Willebrandfrctor r. UPEP urine proteh electrophoresis vzlt raricella-zoster virus I URI upper respiratory tnfection WBC whiteblood cell USPSTF U.S. Preventive Services Task Force WNND West Nile neuroinvasirrc disease i UTI urinary tract infection wNv West Nilevirus VAP ventilator-associated pneumonia wPw Wolff-Parkinson-White i : \ I f, 397