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Walk the evidence base by book and chapter — the raw source passages that ground Ask, Differential, and the rest.
5 passages
Non-evidence-based nutraceuticals (e.g., coenzyme Q10, hair therapies) are low-value in primary care. Why: Nutraceuticals with limited evidence should not be routinely prescribed; they increase cost without proven clinical benefit.
Multi-ingredient supplements for single-nutrient deficiencies are low-value and irrational. Why: Using combination supplements for isolated deficiencies increases cost and risk of unnecessary nutrient intake without added benefit.
Unindicated vitamin D supplementation without documented deficiency is low-value. Why: Routine vitamin D supplementation in non-deficient individuals lacks evidence for benefit and increases healthcare costs.
Prescribing multi-ingredient supplements or nutraceuticals with limited evidence of efficacy is proposed as low-value care. Why: These products often lack robust evidence for their claimed benefits and contribute to unnecessary patient expenditure and polypharmacy.
Prescribing non-evidence-based nutraceuticals or supplements without a documented indication is of low value. Why: This practice adds to patient cost and polypharmacy without proven clinical benefit for the prescribed condition.