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Walk the evidence base by book and chapter — the raw source passages that ground Ask, Differential, and the rest.

• Antithrombin III for critically ill patients: a systematic review with meta-analysis and trial sequential analysis1 passage
• Association between ABCDE bundle compliance and long-term outcomes: a secondary longitudinal analysis1 passage
• Associations between ventilator settings during extracorporeal membrane oxygenation for refractory hypoxemia and outcome in patients with acute respiratory distress syndrome: a pooled individual patient data analysis : Mechanical ventilation during ECMO1 passage
• Between-trial heterogeneity in ARDS research1 passage
• Combined use of a multiplex PCR and serum procalcitonin to reduce antibiotic exposure in critically ill patients with community-acquired pneumonia: the MULTI-CAP randomized controlled trial1 passage
• Comparison of venovenous extracorporeal membrane oxygenation, prone position and supine mechanical ventilation for severely hypoxemic acute respiratory distress syndrome: a network meta-analysis1 passage
• Conservative fluid management or deresuscitation for patients with sepsis or acute respiratory distress syndrome following the resuscitation phase of critical illness: a systematic review and meta-analysis1 passage
• Corticosteroids for adult patients hospitalised with non-viral community-acquired pneumonia: a systematic review and meta-analysis1 passage
• ECMO for severe ARDS: systematic review and individual patient data meta-analysis1 passage
• ESICM guidelines on circulatory shock and hemodynamic monitoring 20251 passage
• ESPNIC clinical practice guidelines: intravenous maintenance fluid therapy in acute and critically ill children- a systematic review and meta-analysis1 passage
• Early enteral nutrition in critically ill patients: ESICM clinical practice guidelines1 passage
• Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis1 passage
• Effect of hydrocortisone on mortality in patients with severe community-acquired pneumonia : The REMAP-CAP Corticosteroid Domain Randomized Clinical Trial1 passage
• Effect of prone positioning on survival in adult patients receiving venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis1 passage
• Effects of restrictive fluid therapy on the time to resolution of hyperlactatemia in ICU patients with septic shock. A secondary post hoc analysis of the CLASSIC randomized trial1 passage
• Electrical impedance tomography-guided positive end-expiratory pressure titration in ARDS: a systematic review and meta-analysis1 passage
• Epidemiology and burden of sepsis acquired in hospitals and intensive care units: a systematic review and meta-analysis1 passage
• European Society of Intensive Care Medicine (ESICM) 2025 clinical practice guideline on fluid therapy in adult critically ill patients: part 2-the volume of resuscitation fluids1 passage
• European Society of Intensive Care Medicine clinical practice guideline on fluid therapy in adult critically ill patients. Part 1: the choice of resuscitation fluids1 passage
• Factors associated with acute mesenteric ischemia among critically ill ventilated patients with shock: a post hoc analysis of the NUTRIREA2 trial1 passage
• Fludrocortisone dose-response relationship in septic shock: a randomised phase II trial1 passage
• Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 20171 passage
• Heterogenous treatment effect of neuromuscular blocking agents for moderate-to-severe ARDS: a post hoc Markov model re-analysis of the ACURASYS trial1 passage
• Hyperoxia during cardiopulmonary bypass does not decrease cardiovascular complications following cardiac surgery: the CARDIOX randomized clinical trial1 passage
• Hypotension during intensive care stay and mortality and morbidity: a systematic review and meta-analysis1 passage
• Immune enhancement in patients with predicted severe acute necrotising pancreatitis: a multicentre double-blind randomised controlled trial1 passage
• Implementation of a kidney protection strategy to prevent acute kidney injury after major surgery in high-risk patients identified by biomarkers: a systematic review and individual participant data meta-analysis of randomized controlled trials1 passage
• Incidence and associations of acute kidney injury after major abdominal surgery1 passage
• Incidence and mortality of hospital- and ICU-treated sepsis: results from an updated and expanded systematic review and meta-analysis1 passage
• Integrative omics provide biological and clinical insights into acute respiratory distress syndrome1 passage
• Liberal vs. restrictive transfusion strategies for acute brain injury: a systematic review and frequentist-Bayesian meta-analysis1 passage
• Long-term outcomes of patients supported with extracorporeal membrane oxygenation for acute respiratory distress syndrome: a systematic review and meta-analysis1 passage
• Low-dose methylprednisolone treatment in critically ill patients with severe community-acquired pneumonia1 passage
• Machine learning for the prediction of sepsis: a systematic review and meta-analysis of diagnostic test accuracy1 passage
• Neuromuscular blockade in patients with ARDS: a rapid practice guideline1 passage
• Noninvasive ventilation on reintubation in patients with obesity and hypoxemic respiratory failure following abdominal surgery: a post hoc analysis of a randomized clinical trial1 passage
• Passive leg raising for predicting fluid responsiveness: a systematic review and meta-analysis1 passage
• Personalized positive end-expiratory pressure in spontaneously breathing patients with acute respiratory distress syndrome by simultaneous electrical impedance tomography and transpulmonary pressure monitoring: a randomized crossover trial1 passage
• Pharmacological principles guiding prolonged glucocorticoid treatment in ARDS1 passage
• Pressure control plus spontaneous ventilation versus volume assist-control ventilation in acute respiratory distress syndrome. A randomised clinical trial1 passage
• Restricted fluid resuscitation in suspected sepsis associated hypotension (REFRESH): a pilot randomised controlled trial1 passage
• Scorpion envenomation: state of the art1 passage
• Sodium chloride or Plasmalyte-148 evaluation in severe diabetic ketoacidosis (SCOPE-DKA): a cluster, crossover, randomized, controlled trial1 passage
• Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 20261 passage
• Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 20161 passage
• Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19)1 passage
• Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children1 passage
• Vasopressin in septic shock: an individual patient data meta-analysis of randomised controlled trials1 passage