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Goal-directed perioperative haemodynamic therapy: need for a modern perioperative care loop. Using GRADE and modified Delphi methods, international experts in haemodynamic management from the Perioperative Operative Quality Initiative (POQI) group presented an updated consensus statement on goal-directed haemodynamic therapy. They do not recommend routine use of goal-directed haemodynamic therapy for major abdominal surgery, or fixed low-dose infusions of inotropes. They recommend goal-directed haemodynamic therapy only in specific settings such as during cardiopulmonary bypass, after cardiac surgery, and for hip fracture surgery, all with a low level of evidence. This approach has implications for future perioperative research.