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Predicting arterial pressure without prejudice: towards effective hypotension prediction models. Selection bias has been identified in hypotension prediction models, but its impact on an algorithm's ability to learn relevant information from the arterial waveform remains unclear. The recent study by Yang and colleagues sheds considerable light on this by training and evaluating a deep learning prediction model with biased and unbiased data selections. Unbiased training data allowed an algorithm to learn modestly more than just current blood pressure and the bias significantly distorted and inflated the positive predictive value. We discuss these findings and offer suggestions for further developing effective hypotension prediction algorithms.