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The Editors1 highlight the devastating effect of COVID-19 in Latin America and the Caribbean, recognising that pervasive inequality, weak health systems, an over-reliance on foreign manufacturing, and fractured coordination has affected the pandemic response in this region. The pandemic unfolds as this region faces extraordinary political divisions, both within and across countries. The Pan American Health Organization (PAHO) has worked closely with governments in Latin America and the Caribbean, providing technical expertise, strengthening health systems, and expanding COVID-19 surveillance.2 Decades of underinvestment in health, however, have limited the capacity of this region to control outbreaks. Greater solidarity, backed by increased health spending and stronger public health systems, is urgently needed.3 There is no way to overcome COVID-19 without vaccines. PAHO is focused on ensuring the region is immunised as quickly as supplies become available. Our revolving fund provides a backbone for vaccine procurement, channelling doses to countries ready to deliver them. Notwithstanding, this region has not been afforded priority in accessing vaccines despite the disproportionate burden of the pandemic there. This situation must change. Latin America and the Caribbean has the expertise and capacity to develop and produce vaccines.4 PAHO will continue to support countries and stakeholders in knowledge sharing, technology transfer, and investment to substantially increase vaccine production.5

Notwithstanding, this region has not been afforded priority in accessing vaccines despite the disproportionate burden of the pandemic there. This situation must change. Latin America and the Caribbean has the expertise and capacity to develop and produce vaccines.4 PAHO will continue to support countries and stakeholders in knowledge sharing, technology transfer, and investment to substantially increase vaccine production.5 Now more than ever, we must work together with a commitment to Pan-Americanism, and to make the investments for more resilient and equitable health systems and societies in the Americas. © 2021 Camilo Freedman/SOPA Images/LightRocket/Getty Images2021