Browse the corpus

2-octyl cyanoacrylate is one of the most commonly used commercially available wound adhesives. Current indications include any easily approximated surgical incision wound or properly cleaned lacerations from trauma in dry areas and have minimal friction. Additionally, 2-octyl cyanoacrylate is approved for use in combination with subcuticular sutures for deeper or higher tension wounds, though its use in higher tension areas should be limited to immobilized areas. This activity reviews the indications, contraindications, administration, and adverse effects of 2-octyl cyanoacrylate for wound closure and highlights the role of the interprofessional team in the effective use of this substance. Objectives: Identify the indications and contraindications for the usage of 2-octyl cyanoacrylate. Explain how to use 2-octyl cyanoacrylate for wound closure. Summarize the risk of wound infection associated with 2-octyl cyanoacrylate for wound closure with that of suture repair. Review how an interprofessional approach to care can improve the application of 2-octyl cyanoacrylate and render therapy more efficient and effective. Access free multiple choice questions on this topic.

The earliest precursors of 2-octyl cyanoacrylate, including ethyl-2 cyanoacrylate, had similar bonding capabilities but rapidly broke down into cyanoacetate and formaldehyde, leading to local inflammatory reactions. 2-octyl cyanoacrylate has overcome this issue by utilizing longer chain products leading to a slower release that can undergo safer, natural excretion. Those who have a hypersensitivity to cyanoacrylate or formaldehyde can develop contact dermatitis if 2-octyl cyanoacrylate is applied.

The practical application of 2-octyl cyanoacrylate is most efficient with an interprofessional approach among the healthcare team, especially in pediatrics. Assistance in irrigating, applying, and securing the patient, if needed, is best shared among nursing, physicians, and patient care technicians. This wound care process is where specialized wound-care nurses can play a significant role in ensuring proper care of the wound, as well as training other ancillary personnel and providing patient education on follow-up wound care.  They are also in a position to recognize any issues or concerns that may arise and report these promptly to the physician managing the case. This type of interprofessional coordination between clinicians (MDs, DOs, PAs, NPs), nurses, and other ancillary staff on the healthcare team is essential when using 2-octyl cyanoacrylate successfully, leading to improved patient care and outcomes. [Level 5]