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Walk the Even Hospital Database by book and chapter — the raw source passages that ground Ask, DDx, and the rest.

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introductionstatpearls· Introduction· item NBK556056

Renin is an aspartyl protease released by the juxtaglomerular cells of the kidneys in response to perceived low blood pressure and renal perfusion. It plays an essential role in the rate-limiting step of the renin-angiotensin-aldosterone system (RAAS), responsible for blood volume homeostasis and mean arterial blood pressure. Renin also acts as a hormone, binding to pro-renin receptors, causing an increase in the conversion of angiotensinogen to angiotensin I.[1][2]