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Famciclovir is a medication used in the management and treatment of herpes and varicella-zoster infections. It is in the class of nucleoside analog antiviral drugs. This activity reviews the indications, action, and contraindications for famciclovir as a valuable agent in managing herpes and varicella-zoster infections. This activity will highlight the mechanism of action, adverse event profile, and other key factors pertinent for members of the healthcare team in the management and care of patients with herpes and varicella-zoster infections and related conditions. Objectives: Describe the treatment considerations for patients with herpes or varicella-zoster infections. Identify the most common adverse events associated with famciclovir therapy. Summarize the risks associated with initiating famciclovir treatment and summarize key patient counseling points. Outline the importance of improving care coordination amongst the interprofessional team to improve outcomes for patients receiving famciclovir treatment. Access free multiple choice questions on this topic.

There are no significant toxic side effects associated with famciclovir treatment, and thus there is no antidote. If a patient taking famciclovir experiences any side effects or suspects toxic effects, they should consult with their doctor as early as possible. Famciclovir is safe to take in patients with acute renal impairment.[2]

Famciclovir has many benefits in terms of ease and effectiveness in treating zoster infections. Therapy with famciclovir is best when under the direction of an interprofessional healthcare team. Famciclovir requires a prescription from a clinician. Famciclovir is a relatively safe antiviral treatment with rare adverse side effects. However, the prescribing clinician must monitor treatment with famciclovir to ensure that the patient does not experience any adverse effects. All primary care clinicians and dermatologists can prescribe famciclovir. To achieve the best results with the treatment, the patient must begin taking famciclovir treatment as soon as possible as the first signs of herpetic or varicella infections occur. Regular follow-ups with patients taking famciclovir suggest that the treatment is working properly and that there are decreased signs of infection. A pharmacist should be involved to ensure that proper dosing of famciclovir is prescribed, and the patient fully understands the treatment regimen. If the patient has any questions regarding treatment, a nurse will be able to answer most questions. Any serious concerns will be discussed between the nurse, doctor, and patient to decide how to alter care. [Level 5]