Browse the corpus
Walk the Even Hospital Database by book and chapter — the raw source passages that ground Ask, DDx, and the rest.
1 passage
©2013 UpToDate ® Print Email Role of angiotensin II in autoregulation of GFR Effect of reducing renal artery pressure (from a baseline value of about 125 mmHg) on glomerular filtrartion rate (GFR), expressed as a percentage of control values in dogs fed a normal sodium diet. The blue squares represent control animals in which both GFR was maintained until the pressure was markedly reduced. The red circles represent animals given an intrarenal infusion of an angiotensin II antagonist; autoregulation of GFR was less well-regulated. Although not shown, autoregulation also applies to GFR when the renal artery pressure is initially raised and to renal blood flow, which is not impaired by inhibiting the activity of angiotensin II. Data from: Hall JE, Guyton AC, Jackson TE, et al. Am J Physiol 1977; 233:F366.