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OR Medium dose inhaled glucocorticoid • plus long-acting beta agonist Δ , if needed Severe persistent High dose inhaled glucocorticoid • plus long-acting beta agonist Δ Prednisone if needed * Albuterol is preferred inhaled short acting beta2 agonist during pregnancy. • Budesonide is preferred inhaled corticosteroid during pregnancy. Δ Salmeterol is preferred long-acting beta agonist during pregnancy. Based on data from: Quick Reference. NAEPP Expert Panel Report Managing Asthma During Pregnancy: Recommendations for Pharmacologic Treatment-Update 2004. US Dept of Health and Human Services, Bethesda, MD. NIH Publication No. 04-5246, March, 2004.