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©2013 UpToDate ® Print Email ACE inhibitor improves survival in advanced HF Decreased mortality in patients with advanced NYHA class III or IV heart failure after treatment with enalapril compared to placebo (p = 0.003). Data from: The CONSENSUS Trial Study Group, N Engl J Med 1987; 316:1429. ACE inhibitor improves survival in moderate HF Enalapril, compared to placebo, decreases patient mortality in NYHA class II and III heart failure (p = 0.0036). Data from: The SOLVD Investigators, N Engl J Med 1991; 325:293. Enalapril improves outcome in asymptomatic LV dysfunction In the SOLVD prevention trial of 4228 patients (83 percent post-MI) with asymptomatic left ventricular dysfunction, prophylactic administration of enalapril reduced the probability of death or heart failure (p <0.001). Data from: The SOLVD Investigators. N Engl J Med 1992; 327:685.
©2013 UpToDate ® Print Email ACE inhibitor improves survival in advanced HF Decreased mortality in patients with advanced NYHA class III or IV heart failure after treatment with enalapril compared to placebo (p = 0.003). Data from: The CONSENSUS Trial Study Group, N Engl J Med 1987; 316:1429.