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Walk the Even Hospital Database by book and chapter — the raw source passages that ground Ask, DDx, and the rest.
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©2013 UpToDate ® Print Email American College of Rheumatology 20 percent improvement criteria (ACR20) [1] At least 20 percent improvement in 1. Swollen joint counts 2. tender joint count and three of the following five variables: 3. Patient assessed global disease activity (eg, by VAS) 4. Evaluator assessed global disease activity (eg, by VAS) 5. Patient pain assessment (eg, by VAS) 6. Functional disability (eg, by HAQ) 7. Acute phase response (ESR or CRP) A 50 percent and 70 percent ACR response (ACR50 and ACR70, respectively) represents respective improvement of at least 50 perecent or at least 70 percent. [2] References: Felson, DT, Anderson, JJ, Boers, M, Bombardier, C, et al. American College of Rheumatology preliminary definition of improvement in rheumatoid arthritis. Arthritis Rheum 1995; 38:727. Felson, DT, Anderson, JJ, Lange, ML, et al. Should improvement in rheumatoid arthritis clinical trials be defined as fifty percent or seventy percent improvement in core set measures, rather than twenty percent?. Arthritis Rheum 1998; 41:1564.