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Walk the Even Hospital Database by book and chapter — the raw source passages that ground Ask, DDx, and the rest.
1 passage
©2013 UpToDate ® Print Email Common mechanisms of antiepileptic drug action Drug Na+ channels Ca+ channels K+ channels Inhibitory transmission Excitatory transmission Benzodiazepines +++ Carbamazepine +++ + Clobazam +++ Ethosuximide +++ Ezogabine ++ Felbamate ++ + ++ ++ Gabapentin + + ++ Lacosamide +++ Lamotrigine +++ + Levetiracetam + + + + Oxcarbazepine +++ + + Perampanel +++ Phenobarbital + +++ + Phenytoin +++ + Rufinamide +++ Tiagabine +++ Topiramate ++ ++ ++ ++ Valproate + + ++ + Vigabatrin +++ Zonisamide ++ ++ +++: primary action; ++: probable action; +: possible action. Adapted with permission from: Brodie MJ, Kwan P. Staged approach to epilepsy management. Neurology 2002; 58:S2. Copyright © 2002 Lippincott Williams & Wilkins.