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©2013 UpToDate ® Print Email Histologic features of acute generalized exanthematous pustulosis (AGEP) Histologic sections of skin show epidermal acanthosis with spongiosis and microvesicle and pustule formation. The dermis shows a perivascular and interstitial infiltrate, extending to mid-reticular dermal levels. Copyright © Greg Hosler, MD, PhD, Dermatlas; file://www.dermatlas.org.
©2013 UpToDate ® Print Email Histologic features of acute generalized exanthematous pustulosis (AGEP) Histologic sections of skin show epidermal acanthosis with spongiosis and microvesicle and pustule formation. The dermis shows a perivascular and interstitial infiltrate, extending to mid-reticular dermal levels. Copyright © Greg Hosler, MD, PhD, Dermatlas; file://www.dermatlas.org. Histopathologic features of acute generalized exanthematous pustulosis (AGEP) This higher power field shows epidermal spongiosis with exocytosis of neutrophils and eosinophils. Small microvesicles/microabscesses are developing. In other fields (not shown), there is subcorneal pustule formation. Copyright © Greg Hosler, MD, PhD, Dermatlas; file://www.dermatlas.org.