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©2013 UpToDate ® Print Email Anaplastic large cell lymphoma, classical variant Case of the common pattern of anaplastic large cell lymphoma shows cohesive clusters of large tumor cells with chromatin-poor nuclei and prominent nucleoli. Some tumor cells reveal the characteristic kidney-shaped nucleus (arrow). Hematoxylin and eosin, 40x magnification. Reproduced with permission from: Sun T. Flow Cytometry, Immunohistochemistry, and Molecular Genetics for Hematologic Neoplasms, 2nd ed, Lippincott Williams & Wilkins, Philadelphia 2012. Copyright © 2012 Lippincott Williams & Wilkins. file://www.lww.com