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©2013 UpToDate ® Email Phonocardiogram of aortic regurgitation as heard at the second right intercostal space Carotid artery pulse tracing and phonocardiogram of aortic regurgitation as heard at the second right intercostal space. S1 (mitral and tricuspid valve closure) is followed by a systolic ejection murmur due to the large stroke volume seen in aortic regurgitation. After S2 (aortic and pulmonic valve closure) there is a faint and short diastolic "blowing" murmur of aortic regurgitation. Provided by John M Criley, MD, The Physiological Origins of Heart Sounds and Murmurs, Little, Brown, Boston, 1996, 1-800-527-0145. This program contains a complete interactive tutorial integrating over 200 heart sounds and murmurs with cineangiographic, echo-Doppler, and hemodynamic motion picture sequences.