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©2013 UpToDate ® Print Email Long-term postoperative survival in aortic regurgitation Patients with aortic regurgitation who are in functional class I or II before surgery have a survival after surgery that is similar to that expected in an age and gender matched normal population. In contrast, the outcome among patients who are in functional class III or IV before surgery is worse than for those with functional class I and II (p Data from Klodas, E, Enriquez-Sarano, M, Tajik, AJ, et al, J Am Coll Cardiol 1997; 30:746.