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©2013 UpToDate ® Print Email Guidelines for the use of droperidol for endoscopic procedures Use only in select patients with: Anticipated intolerance of standard sedatives Anticipated long procedure time Obtain 12-lead ECG. Droperidol is contraindicated if the QTc is prolonged (>440 msec males, >450 msec females). Patients should remain on a cardiac monitor during the procedure and for 2 to 3 hours afterward Use with caution in patients at risk for development of prolonged QT syndrome: HF, bradycardia, cardiac hypertrophy, hypokalemia/magnesemia, on other drugs known to prolong the QT interval Dosage: in adults the initial dosage should not exceed 2.5 mg. Additional doses should be in 1.25 mg aliquots to achieve the desired effect. Maximum dose: 5 mg. Reproduced with permission from: Faigel DO, Baron TH, Goldstein JL, et al. Guidelines for the use of deep sedation and anesthesia for GI endoscopy. Gastrointest Endosc 2002; 56:613. Copyright © 2002 Elsevier Science.