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©2013 UpToDate ® Print Email Acanthosis nigricans Classic hyperpigmented axillary lesion in acanthosis nigricans. Courtesy of Jeffrey Flier, MD. Acanthosis nigricans A velvety, slightly verrucous plaque is present on the neck.

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Gregoriou S, Anyfandakis V, Kontoleon P, et al. Acanthosis nigricans associated with primary hypogonadism: successful treatment with topical calcipotriol. J Dermatolog Treat 2008; 19:373. Rosenbach A, Ram R. Treatment of Acanthosis nigricans of the axillae using a long-pulsed (5-msec) alexandrite laser. Dermatol Surg 2004; 30:1158. Swineford SL, Drucker CR. Palliative treatment of paraneoplastic acanthosis nigricans and oral florid papillomatosis with retinoids. J Drugs Dermatol 2010; 9:1151. Katz RA. Treatment of acanthosis nigricans with oral isotretinoin. Arch Dermatol 1980; 116:110. Bonnekoh B, Thiele B, Merk H, Mahrle G. [Systemic photochemotherapy (PUVA) in acanthosis nigricans maligna: regression of keratosis, hyperpigmentation and pruritus]. Z Hautkr 1989; 64:1059. Greenwood R, Tring FC. Treatment of malignant acanthosis nigricans with cyproheptadine. Br J Dermatol 1982; 106:697. CURTH HO, HILBERG AW, MACHACEK GF. The site and histology of the cancer associated with malignant acanthosis nigricans. Cancer 1962; 15:364. Topic 13754 Version 1.0 © 2013 UpToDate, Inc. All rights reserved. | Subscription and License Agreement | Release: 21.6- C21.56 Licensed to: AsanBook Dig. Med. Lib. | Support Tag: [1103-89.32.226.102-C070ECA3F8-S244013.14]