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contentuptodate· Content· item f14_4_14414
©2013 UpToDate ® Print Email Benefit of accelerated t-PA in acute myocardial infarction The overall one-year mortality for patients treated with different thrombolytic strategies in the GUSTO-1 trial. The mortality rate was lower in patients treated with accelerated t-PA compared to those receiving streptokinase and either intravenous (IV) or subcutaneous (SQ) heparin (p = 0.003) or t-PA and streptokinase in combination (p = 0.05). Data from Califf RM, White HD, Van de Werk F, et al for the GUSTO-1 Investigators, Circulation 1996; 94:1233.