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contentuptodate· Content· item f37_37_38487
©2013 UpToDate ® Print Email Histologic grade 2 acute graft-versus-host disease Apoptotic keratinocytes in the epidermis, vacuolization of the basal layer, and lymphocyte exocytosis are present in this specimen of histologic grade 2 acute graft-versus-host disease. A lymphocytic infiltrate at the dermal-epidermal junction and surrounding blood vessels is also present.