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contentuptodate· Content· item f18_2_18468
©2013 UpToDate ® Print Email Acute osteomyelitis Light micrograph of acute osteomyelitis of the tibia shows many disconnected bony trabeculae in a sea of inflammatory cells (red arrow) and a single multinucleated giant cell (black arrow). The surfaces of the trabeculae (white arrows) have a few undifferentiated, spindle-shaped, connective tissue elements. There is little evidence of active bone formation or bone resorption. Courtesy of Jon Mader, MD.