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contentuptodate· Content· item f2_57_2973

©2013 UpToDate ® Print Email Adjuvant analgesics used for cancer pain Category based on conventional use Class Subclass Drugs Multipurpose analgesics Corticosteroids - Dexamethasone, prednisone, methylprednisone Antidepressants Tricyclic Amitriptyline, desipramine, nortriptyline SNRIs Duloxetine, minalcipran, venlafaxine, desvenlafaxine SSRIs Paroxetine, citalopram Other Buproprion Alpha-2 adrenergic agonists - Tizanidine, clonidine Cannabinoids - Dronabinol, nabilone, others Topical analgesics - Local anesthetics capsaicin, tricyclic antidepressants, NSAIDs, others Used for neuropathic pain All multipurpose analgesics See above See above Anticonvulsants - Gabapentin, pregabalin, valproate, phenytoin, carbamazepine, oxcarbazepine, topiramate, lamotrigine, tiagabine Sodium channel blockers Sodium channel modulator Lacosamide Sodium channel blocker Mexiletine, IV lidocaine N-methyl-D-aspartate receptor antagonists - Ketamine, memantine, dextromethorphan, amantadine GABA agonists GABA a agonists Clonazepam GABA b agonists Baclofen Used for bone pain Osteoclast inhibitors Bisphosphonates Pamidronate, zolendronate, ibandronate - Calcitonin Radiopharmaceuticals Plus: NSAIDs, corticosteroids - Strontium-89, samarium-153 Used for bowel obstruction Anticholinergic drugs - Scopolamine, atropine, glycopyrrolate Somatostatin analogue Plus: Corticosteroids - Octreotide GABA: gamma amino butyric acid.