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©2013 UpToDate ® Print Email Adjustments in subcutaneous immunotherapy dosing for gaps in treatment Build-up phase Up to 7 days late Continue build-up as scheduled 8 to 13 days late Repeat previous dose 14 to 21 days late Reduce dose 25 percent 21 to 28 days late Reduce dose 50 percent Maintenance phase 2 to 4 weeks late Reduce dose 75 percent >4 weeks late Reduce by one or more dilutions depending on length of time and patient sensitivity