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©2013 UpToDate ® Print Email The advantages of the main treatment options for early prostate cancer External beam radiation therapy Effective long-term cancer control with high-dose treatments Very low risk of urinary incontinence Available for cure of patients over a wide range of ages and in those with significant comorbidity Combined with hormone therapy treatment, offers an improved chance for a cure in high-risk disease Treatments can eradicate extensions of tumor beyond the margins of the prostate Brachytherapy Cancer control rates appear equal to surgery and EBRT for organ-confined tumors Quicker than EBRT (single treatment) Risk of incontinence is low in patients without a previous TURP Available for cure of patients over a wide range of ages and in those with some comorbidity Radical prostatectomy Effective long-term cancer control Predictions of prognosis can be more precise based on pathologic features in specimen Pelvic lymph node dissection is possible through the same incision PSA failure is easy to detect Active observation Reduces overtreatment Avoids or postpones treatment-associated complications Has no effect on work or social activities TURP: transurethral resection of the prostate; EBRT: external beam radiation therapy. Reproduced with permission from: Vogelzang NJ, Scardino PT, Shipley WU, et al. Comprehensive textbook of genitourinary oncology, 3rd Edition. Lippincott Williams & Wilkins 2005. Copyright © 2005 Lippincott Williams & Wilkins. file://www.lww.com