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Walk the Even Hospital Database by book and chapter — the raw source passages that ground Ask, DDx, and the rest.
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©2013 UpToDate ® Print Email Aggressive BP control preserves renal function in proteinuric patients Mean fall in glomerular filtration rate (GFR) according to the degree of proteiuria in patients treated with usual blood pressure control (mean BP about 130/80) or with more aggressive antihypertensive therapy in which the mean BP was 4.7 mmHg lower over a three year period. The rate of fall in GFR varied directly with protein excretion and the benefit of aggressive BP control was absent in the 420 patients excreting less than 1 g/day, modest in the 104 patients excreting between 1 and 3 g/day, and substantial (3.5 mL/min per year slower) and statistically significant in the 54 patients excreting at least 3 g/day. Data from: Klahr S, Levey AS, Beck GJ, et al. N Engl J Med 1994; 330:877.