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Walk the Even Hospital Database by book and chapter — the raw source passages that ground Ask, DDx, and the rest.
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©2013 UpToDate ® Print Email Physiologic agonists for platelet activation and their respective receptors on the platelet surface Agonist Source Receptor(s) Thrombin End product of coagulation cascade 7 transmembrane domainreceptor GPIb-alpha Adenosine dephosphate Platelet dense body Aggregin Collagen Subendothelium component GPIa/IIa GPIIb/IIIa GPIV Serotonin Platelet dense body 5HT2 receptor Thromboxane A2 Produced by platelets after initial stimulation PGH2/TxA2 receptor Platelet activating factor Lipid mediator produced by other cells PAF receptor GP: glycoprotein; HT: hydroxytryptamine, serotonin; PG: prostaglandin; Tx: thromboxane