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©2013 UpToDate ® Print Email Plasma albumin in nephrotic syndrome and CAPD Relationship between total albumin loss and the plasma albumin concentration in patients undergoing continuous ambulatory peritoneal dialysis (CAPD), in which albumin is primarily lost in the dialysate fluid, and those with the nephrotic syndrome. At any level of albumin loss, the plasma albumin concentration is approximately 1 g/dL (10 g/L) lower in patients with the nephrotic syndrome, suggesting that some factor in addition to urinary albumin excretion must be involved. Data from Kaysen, GA, Schoenfeld, PY, Kidney Int 1984; 25:107.