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©2013 UpToDate ® Print Email Diagnostic algorithm for palpable breast abnormalities in women aged 30 years and over When lesions are palpable, clinically directed biopsies are often the most efficient. Fine-needle aspiration (FNA) is the biopsy of choice, but if it is not available or reliable at an institution, percutaneous core biopsy can easily be substituted. BI-RADS: Breast Imaging Reporting and Data System; U/S: ultrasound; FNA: fine-needle aspiration. * The asterisk indicates a situation in which it may be useful to incorporate a staging MRI into the management of a patient with breast cancer if this technique is available. Adapted from Esserman, L, et al. Current Oncology Reports 2000; 2:572.