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©2013 UpToDate ® Print Email Algorithm for management of patients with PPROM * Expectant management includes prophylactic antibiotics, corticosteroids (if fetal pulmonary immaturity), a 48 hour course of tocolytics to administer corticosteroids in patients with preterm labor and suspected pulmonary immaturity, and surveillance for maternal infection and fetal compromise. With rare exceptions, most patients will be delivered by 36 weeks of gestation.