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©2013 UpToDate ® Print Email Controlled trials of allergen avoidance that have achieved prolonged decrease in mite allergen Authors Time Avoidance Active/controls Decrease in mite Primary outcome(s) Murray, AB, Ferguson, AC; Pediatrics 1983; 71:418 1 yr Physical barriers 10/10 ++ BHR** Carswell et al.; Clin Exp Allergy 1996; 26:386 6 mos Physical barriers + Acarosan 24/25 + Peak flow• BHR• Ehnert, B, et al.; J Allergy Clin Immunol 1992; 90:135 1 yr Physical barriers + tannic acid 8/16 ++ BHR** Walshaw, MJ, Evans, CC; Q J Med 1986; 58:199 1 yr Physical barriers 22/20 ++ PEFR/BHR** Halken et al.; J Allergy Clin Immunol 1997; 99:S320 1 yr Physical barriers 28/24 ++ PEFR**BHR* Htut, T, et al.; J Allergy Clin Immunol 2001; 107:55. 1 yr Dry heat and steam cleaning 20/10 ++ BHR* Improvement: ** Highly significant; * Significant; • improved but not significant.