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REFERENCES Shah A, Panjabi C. Human seminal plasma allergy: a review of a rare phenomenon. Clin Exp Allergy 2004; 34:827. Best CL, Walters C, Adelman DC. Fixed cutaneous eruptions to seminal-plasma challenge: a case report. Fertil Steril 1988; 50:532. Mike N, Bird G, Asquith P. A new manifestation of seminal fluid hypersensitivity. Q J Med 1990; 75:371. Mathias CG, Frick OL, Caldwell TM, et al. Immediate hypersensitivity to seminal fluid and atopic dermatitis. Arch Dermatol 1980; 116:209. Bernstein JA, Sugumaran R, Bernstein DI, Bernstein IL. Prevalence of human seminal plasma hypersensitivity among symptomatic women. Ann Allergy Asthma Immunol 1997; 78:54. Ohman JL Jr, Malkiel S, Lewis S, Lorusso JR. Allergy to human seminal fluid: characterization of the allergen and experience with immunotherapy. J Allergy Clin Immunol 1990; 85:103. Bajardeen B, Melendez J, Yoong W. Human seminal plasma hypersensitivity: an unusual indication for in vitro fertilization. Eur J Obstet Gynecol Reprod Biol 2010; 153:226. Ebo DG, Stevens WJ, Bridts CH, De Clerck LS. Human seminal plasma anaphylaxis (HSPA): case report and literature review. Allergy 1995; 50:747. Ferré-Ybarz L, Basagaña M, Coroleu B, et al. Human seminal plasma allergy and successful pregnancy. J Investig Allergol Clin Immunol 2006; 16:314. Song WJ, Kim DI, Kim MH, et al. Human seminal plasma allergy: successful pregnancy after prophylactic anti-histamine treatment. Asia Pac Allergy 2011; 1:168. Nist GC, von den Driesch P. Human seminal plasma allergy--a rare cause of recurrent anaphylaxis. J Dtsch Dermatol Ges 2007; 5:34. Mittman RJ, Bernstein DI, Adler TR, et al. Selective desensitization to seminal plasma protein fractions after immunotherapy for postcoital anaphylaxis. J Allergy Clin Immunol 1990; 86:954. Frisch C, Pujade-Lauraine MD, Leynadier F, Dry J. Rush hyposensitisation for allergy to seminal plasma. Lancet 1984; 1:1073. Bernstein IL, Englander BE, Gallagher JS, et al. Localized and systemic hypersensitivity reactions to human seminal fluid. Ann Intern Med 1981; 94:459. Chang TW. Familial allergic seminal vulvovaginitis. Am J Obstet Gynecol 1976; 126:442. Kint B, Degreef H, Dooms-Goossens A. Combined allergy to human seminal plasma and latex: case report and review of the literature. Contact Dermatitis 1994; 30:7. Levine BB, Siraganian RP, Schenkein I. Allergy to human seminal plasma. N Engl J Med 1973; 288:894.

Chang TW. Familial allergic seminal vulvovaginitis. Am J Obstet Gynecol 1976; 126:442. Kint B, Degreef H, Dooms-Goossens A. Combined allergy to human seminal plasma and latex: case report and review of the literature. Contact Dermatitis 1994; 30:7. Levine BB, Siraganian RP, Schenkein I. Allergy to human seminal plasma. N Engl J Med 1973; 288:894. Weidinger S, Mayerhofer A, Raemsch R, et al. Prostate-specific antigen as allergen in human seminal plasma allergy. J Allergy Clin Immunol 2006; 117:213. Basagaña M, Bartolomé B, Pastor C, et al. Allergy to human seminal fluid: cross-reactivity with dog dander. J Allergy Clin Immunol 2008; 121:233. Mattsson L, Lundgren T, Everberg H, et al. Prostatic kallikrein: a new major dog allergen. J Allergy Clin Immunol 2009; 123:362. Bernstein JA. Human seminal plasma hypersensitivity: an under-recognized women's health issue. Postgrad Med 2011; 123:120. The author's program, which is based at the University of Cincinnati College of Medicine, in Cincinnati, Ohio, can be accessed at the URL provided. The author is not aware of other centers in the United States that perform HSP fractionation and subcutaneous immunotherapy. www.Seminalplasmaallergy.org (Accessed on April 02, 2012). Friedman SA, Bernstein IL, Enrione M, Marcus ZH. Successful long-term immunotherapy for human seminal plasma anaphylaxis. JAMA 1984; 251:2684. Bernstein JA, Herd ZA, Bernstein DI, et al. Evaluation and treatment of localized vaginal immunoglobulin E-mediated hypersensitivity to human seminal plasma. Obstet Gynecol 1993; 82:667. Babula O, Bongiovanni AM, Ledger WJ, Witkin SS. Immunoglobulin E antibodies to seminal fluid in women with vulvar vestibulitis syndrome: relation to onset and timing of symptoms. Am J Obstet Gynecol 2004; 190:663. Yocum MW, Jones RT, Yunginger JW. Concurrent sensitization to natural rubber latex and human seminal fluid. J Allergy Clin Immunol 1996; 98:1135. Green RL, Green MA. Postcoital urticaria in a penicillin-sensitive patient. Possible seminal transfer of penicillin. JAMA 1985; 254:531. Paladine WJ, Cunningham TJ, Donavan MA, Dumper CW. Letter: Possible sensitivity to vinblastine in prostatic or seminal fluid. N Engl J Med 1975; 292:52. Lee-Wong M, Collins JS, Nozad C, Resnick DJ. Diagnosis and treatment of human seminal plasma hypersensitivity. Obstet Gynecol 2008; 111:538.

Green RL, Green MA. Postcoital urticaria in a penicillin-sensitive patient. Possible seminal transfer of penicillin. JAMA 1985; 254:531. Paladine WJ, Cunningham TJ, Donavan MA, Dumper CW. Letter: Possible sensitivity to vinblastine in prostatic or seminal fluid. N Engl J Med 1975; 292:52. Lee-Wong M, Collins JS, Nozad C, Resnick DJ. Diagnosis and treatment of human seminal plasma hypersensitivity. Obstet Gynecol 2008; 111:538. Jedrzejczak P, Pawelczyk L. [Pregnancy in a patient with seminal hypersensitivity]. Ginekol Pol 2007; 78:892. Park JW, Ko SH, Kim CW, et al. Seminal plasma anaphylaxis: successful pregnancy after intravaginal desensitization and immunodetection of allergens. Allergy 1999; 54:990. Iwahashi K, Miyazaki T, Kuji N, Yoshimura Y. Successful pregnancy in a woman with a human seminal plasma allergy. A case report. J Reprod Med 1999; 44:391. Lee J, Kim S, Kim M, et al. Anaphylaxis to husband's seminal plasma and treatment by local desensitization. Clin Mol Allergy 2008; 6:13. Matloff SM. Local intravaginal desensitization to seminal fluid. J Allergy Clin Immunol 1993; 91:1230. The author's program for HSP fractionation and desensitization can be accessed through the website listed. The program is based at the University of Cincinnati College of Medicine, Cincinnati, Ohio. The author is not aware of other centers in the United States that have published experience in fractionating HSP. Seminalplasmaallergy.org (Accessed on April 01, 2012). Topic 13529 Version 2.0 © 2013 UpToDate, Inc. All rights reserved. | Subscription and License Agreement | Release: 21.3 - C21.34 Licensed to: Morehouse School of Medicine | Support Tag: [0504-125.39.66.146-1B4384F6EC-S473950.14]