Browse the corpus
Walk the Even Hospital Database by book and chapter — the raw source passages that ground Ask, DDx, and the rest.
1 passage
©2013 UpToDate ® Print Email Alpha and beta globin gene clusters in man Schematic representation of the alpha (lower) and beta (upper) globin gene clusters in man, showing the position of the various genes, as well as the locus control region (LCR) for the beta globin gene cluster and the various hypersensitive sites for the beta globin gene cluster (HS 1 to 5) and the alpha gene cluster (HS-40). The only genes active after birth in the beta globin gene cluster are those for G(gamma), A(gamma), delta, and beta globin, while those active after birth in the alpha globin gene cluster are the two alpha genes (alpha 2 and alpha 1). The hemoglobin A tetramer (HbA) shown between the two clusters is formed from the products of the beta globin gene (on chromosome 11) and the two alpha globin genes (on chromosome 16). Figure drawn by Dr. Ross Hardison and reproduced with permission from the Globin Gene Server, which can be found at: <file://globin.cse.psu.edu>.