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Walk the Even Hospital Database by book and chapter — the raw source passages that ground Ask, DDx, and the rest.

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©2013 UpToDate ® Print Email Feedback loop of the alternative complement pathway After C3b is generated, it binds to factor B. Factor D can then cleave factor B to form the C3 convertase (C3bBb). The attachment of properdin (P) stabilizes the complex. The end result is the deposition of large amounts of C3b on the pathogen. Adapted from: Liszewski, MK, Atkinson, JP. The complement system. In: Immunology Scope Monograph, Schwartz, BD (Ed), Upjohn, Kalamazoo, 1992.