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Walk the Even Hospital Database by book and chapter — the raw source passages that ground Ask, DDx, and the rest.
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©2013 UpToDate ® Print Email Maximum work load progressively decreases at higher altitudes The mean reduction in maximal workload, expressed as percentage decreases from baseline, is shown at various simulated altitudes in healthy subjects (filled squares) and heart failure patients with normal baseline functional capacity (filled circles), slightly diminished baseline functional capacity (filled triangles) and severely impaired capacity (open circles). The reduction in work load in those with stable heart failure is in proportion to the limitation in work load seen at sea level, but is greater in those with heart failure who are severely limited. Data from Agostoni, P, Cattadori, G, Guazzi, M, et al. Effects of Simulated altitude-induced hypoxia on exercise capacity in patients with chronic heart failure. Am J Med 2000; 109:450