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©2013 UpToDate ® Print Email Ambulatory detoxification protocols Reduce moderate withdrawal symptoms and risk for serious withdrawal symptoms - fixed dosing If withdrawal symptoms are moderate (ie, CIWA score between 8 and 15) then use one of the following protocols: Long-acting benzodiazepine protocol - (Chlordiazepoxide) Day 1 - 50 mg every 6 to 12 hours Day 2 - 25 mg every 6 hours Day 3 - 25 mg twice a day Day 4 - 25 mg at night Shorter-acting benzodiazepine protocol (Oxazepam) Day 1 - 30 mg every 6 hours Day 2 - 30 mg every 8 hours Day 3 - 30 mg every 12 hours Day 4 - 30 mg at night Anti-convulsant Protocol (Carbamazepine) Day 1 - 200 mg every 6 hours Day 2 - 200 mg every 8 hours Day 3 - 200 mg every 12 hours Day 4 - 200 mg one dose Reduce or prevent mild withdrawal symptoms - symptom triggered If withdrawal symptoms are not present or mild (ie, CIWA score less than 8) then use one of the following protocols: Long-acting benzodiazepine protocol - (Chlordiazepoxide) Day 1 - 50 mg every 6 to 12 hours as needed Days 2 to 5 - 25 mg every 6 hours as needed Shorter-acting benzodiazepine protocol (Oxazepam) Day 1 - 30 mg every 6 hours as needed Days 2 to 5 - 15 mg every 6 hours as needed Nutritional support Thiamine 100 mg for 3 days, multivitamins maintenance