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©2013 UpToDate ® Print Email Anencephaly at 12 1/7th weeks of gestation A) Sagittal view of the fetus. Note the unusual shape of the fetal head and the lack of surrounding cranium. B) Transverse section showing the abnormal shape of the head, with some dysmorphic brain tissue 'hanging' from the side of the head. The orbits are prominent. The amniotic fluid is echogenic as compared with the extraembryonic space; this is due to tissue debris from the disintegrating brain. C) Three-dimensional ultrasound reconstruction of the fetus demonstrating the abnormal head shape (arrows point to the fetal head). Courtesy of Ana Monteagudo, MD. Anencephaly at 32 postmenstrual weeks of gestation A coronal view of the face. the eyes are prominent and above them no cranial vault or brain tissue is seen (A). A longitudinal view of the neck region and upper thoracic vertebrae showing the disrupted bony structures as well as some disorganized neutral tissue (B). In a transverse view the typical U-shaped vertebrae with tissue protruding is evident. This is consistent with an open upper spina bifida which is commonly seen with anencephaly. Courtesy of Ana Monteagudo, MD.

©2013 UpToDate ® Print Email Anencephaly at 12 1/7th weeks of gestation A) Sagittal view of the fetus. Note the unusual shape of the fetal head and the lack of surrounding cranium. B) Transverse section showing the abnormal shape of the head, with some dysmorphic brain tissue 'hanging' from the side of the head. The orbits are prominent. The amniotic fluid is echogenic as compared with the extraembryonic space; this is due to tissue debris from the disintegrating brain. C) Three-dimensional ultrasound reconstruction of the fetus demonstrating the abnormal head shape (arrows point to the fetal head). Courtesy of Ana Monteagudo, MD.