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©2013 UpToDate ® Print Email Mammogram, CT scan, and MRI angiosarcoma of the breast This 55-year-old patient has angiosarcoma of the left breast secondary to radiation therapy for breast carcinoma eight years prior. She presented with breast enlargement and bluish discoloration of the skin which was clinically initially felt to correspond to an "expanding hematoma". The mammogram of the left breast (A) reveals multiple nodular masses (white arrows) in the outer part of the breast with overall increased trabecular background markings and skin thickening (thick white arrow). The CT scan through the mid chest (B) shows a skin nodule (yellow arrow), breast nodules (white arrows), and thickened skin (thick white arrow) of the left breast. There are increased trabecular background markings throughout the left breast. The T1 weighted fat suppressed MRI post contrast images show three suspiciously enhancing masses (white arrows in C) and thickened and enhancing skin (thick yellow arrow, D). The T1 weighted MRI image in axial projection (E) shows nodular foci of skin thickening (blue arrows). Courtesy of Priscilla J Slanetz, MD, MPH, FACR.