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referencesuptodate· REFERENCES· item f37_62_38890

REFERENCES Mehler PS. Diagnosis and care of patients with anorexia nervosa in primary care settings. Ann Intern Med 2001; 134:1048. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision, American Psychiatric Association, Washington, DC, 2000. Eating Disorders: Core Interventions in the Treatment of and Management of Anorexia Nervosa, Bulimia Nervosa and Related Eating Disorders. National Institute for Clinical Excellence, Clinical Guideline 9. file://guidance.nice.org.uk (Accessed on December 22, 2010). Sullivan PF. Mortality in anorexia nervosa. Am J Psychiatry 1995; 152:1073. Steinhausen HC. The outcome of anorexia nervosa in the 20th century. Am J Psychiatry 2002; 159:1284. Löwe B, Zipfel S, Buchholz C, et al. Long-term outcome of anorexia nervosa in a prospective 21-year follow-up study. Psychol Med 2001; 31:881. Keel PK, Dorer DJ, Eddy KT, et al. Predictors of mortality in eating disorders. Arch Gen Psychiatry 2003; 60:179. Herzog W, Deter HC, Fiehn W, Petzold E. Medical findings and predictors of long-term physical outcome in anorexia nervosa: a prospective, 12-year follow-up study. Psychol Med 1997; 27:269. World Health Organization. The ICD-10 Classification of Mental and Behavioral Disorders: Clinical Descriptions and Diagnostic Guidelines. file://www.who.int/classifications/icd/en/bluebook.pdf (Accessed on December 07, 2010). American Psychiatric Association. Treatment of patients with eating disorders,third edition. American Psychiatric Association. Am J Psychiatry 2006; 163:4. Fuentebella J, Kerner JA. Refeeding syndrome. Pediatr Clin North Am 2009; 56:1201. Boateng AA, Sriram K, Meguid MM, Crook M. Refeeding syndrome: treatment considerations based on collective analysis of literature case reports. Nutrition 2010; 26:156. Miller KK, Grinspoon SK, Ciampa J, et al. Medical findings in outpatients with anorexia nervosa. Arch Intern Med 2005; 165:561. Mitchell JE, Crow S. Medical complications of anorexia nervosa and bulimia nervosa. Curr Opin Psychiatry 2006; 19:438. Olivares JL, Vázquez M, Fleta J, et al. Cardiac findings in adolescents with anorexia nervosa at diagnosis and after weight restoration. Eur J Pediatr 2005; 164:383. Cooke RA, Chambers JB, Singh R, et al. QT interval in anorexia nervosa. Br Heart J 1994; 72:69.

referencesuptodate· REFERENCES· item f37_62_38890

Mitchell JE, Crow S. Medical complications of anorexia nervosa and bulimia nervosa. Curr Opin Psychiatry 2006; 19:438. Olivares JL, Vázquez M, Fleta J, et al. Cardiac findings in adolescents with anorexia nervosa at diagnosis and after weight restoration. Eur J Pediatr 2005; 164:383. Cooke RA, Chambers JB, Singh R, et al. QT interval in anorexia nervosa. Br Heart J 1994; 72:69. Goldberg SJ, Comerci GD, Feldman L. Cardiac output and regional myocardial contraction in anorexia nervosa. J Adolesc Health Care 1988; 9:15. Mehler PS, Winkelman AB, Andersen DM, Gaudiani JL. Nutritional rehabilitation: practical guidelines for refeeding the anorectic patient. J Nutr Metab 2010; 2010. Johnson GL, Humphries LL, Shirley PB, et al. Mitral valve prolapse in patients with anorexia nervosa and bulimia. Arch Intern Med 1986; 146:1525. Freed LA, Levy D, Levine RA, et al. Prevalence and clinical outcome of mitral-valve prolapse. N Engl J Med 1999; 341:1. Mehler PS, Krantz M. Anorexia nervosa medical issues. J Womens Health (Larchmt) 2003; 12:331. Isner JM, Roberts WC, Heymsfield SB, Yager J. Anorexia nervosa and sudden death. Ann Intern Med 1985; 102:49. Mehler PS, Lezotte D, Eckel R. Lipid levels in anorexia nervosa. Int J Eat Disord 1998; 24:217. Frölich J, von Gontard A, Lehmkuhl G, et al. Pericardial effusions in anorexia nervosa. Eur Child Adolesc Psychiatry 2001; 10:54. Docx MK, Gewillig M, Simons A, et al. Pericardial effusions in adolescent girls with anorexia nervosa: clinical course and risk factors. Eat Disord 2010; 18:218. Melanson EL, Donahoo WT, Krantz MJ, et al. Resting and ambulatory heart rate variability in chronic anorexia nervosa. Am J Cardiol 2004; 94:1217. Casiero D, Frishman WH. Cardiovascular complications of eating disorders. Cardiol Rev 2006; 14:227. Kanbur NO, Goldberg E, Pinhas L, et al. Second-degree atrioventricular block (Mobitz Type I) in an adolescent with anorexia nervosa: intrinsic or acquired conduction abnormality. Int J Eat Disord 2009; 42:575. Ulger Z, Gürses D, Ozyurek AR, et al. Follow-up of cardiac abnormalities in female adolescents with anorexia nervosa after refeeding. Acta Cardiol 2006; 61:43. Walder A, Baumann P. Cardiac left bundle branch block and pancytopenia in anorexia nervosa: higher risk with mirtazapine and pantoprazole? Case report. Pharmacopsychiatry 2009; 42:79.

referencesuptodate· REFERENCES· item f37_62_38890

Ulger Z, Gürses D, Ozyurek AR, et al. Follow-up of cardiac abnormalities in female adolescents with anorexia nervosa after refeeding. Acta Cardiol 2006; 61:43. Walder A, Baumann P. Cardiac left bundle branch block and pancytopenia in anorexia nervosa: higher risk with mirtazapine and pantoprazole? Case report. Pharmacopsychiatry 2009; 42:79. Bravender T, Kanter R, Zucker N. Anorexia nervosa and second-degree atrioventricular block (Type I). Int J Eat Disord 2006; 39:612. Krantz MJ, Donahoo WT, Melanson EL, Mehler PS. QT interval dispersion and resting metabolic rate in chronic anorexia nervosa. Int J Eat Disord 2005; 37:166. Mehler PS, Krantz MJ. QT dispersion in anorexia nervosa. Am J Cardiol 2005; 96:1034. Mont L, Castro J, Herreros B, et al. Reversibility of cardiac abnormalities in adolescents with anorexia nervosa after weight recovery. J Am Acad Child Adolesc Psychiatry 2003; 42:808. Mehler, PS, Birmingham, LC, Crow, SJ, Jahraus, JP. Medical complications of eating disorders. In: The Treatment of Eating Disorders: A Clinical Handbook, Grilo, CM, Mitchell, JE (Eds), The Guilford Press, New York 2010. p.66. Roche F, Barthélémy JC, Mayaud N, et al. Refeeding normalizes the QT rate dependence of female anorexic patients. Am J Cardiol 2005; 95:277. Facchini M, Sala L, Malfatto G, et al. Low-K+ dependent QT prolongation and risk for ventricular arrhythmia in anorexia nervosa. Int J Cardiol 2006; 106:170. Awazu M, Matsuoka S, Kamimaki T, et al. Absent circadian variation of blood pressure in patients with anorexia nervosa. J Pediatr 2000; 136:524. Galetta F, Franzoni F, Prattichizzo F, et al. Heart rate variability and left ventricular diastolic function in anorexia nervosa. J Adolesc Health 2003; 32:416. Derman T, Szabo CP. Why do individuals with anorexia die? A case of sudden death. Int J Eat Disord 2006; 39:260. Krantz MJ, Mehler PS. Resting tachycardia, a warning sign in anorexia nervosa: case report. BMC Cardiovasc Disord 2004; 4:10. Shamim T, Golden NH, Arden M, et al. Resolution of vital sign instability: an objective measure of medical stability in anorexia nervosa. J Adolesc Health 2003; 32:73. Katz MG, Vollenhoven B. The reproductive endocrine consequences of anorexia nervosa. BJOG 2000; 107:707. Waller K, Swan SH, Windham GC, et al. Use of urine biomarkers to evaluate menstrual function in healthy premenopausal women. Am J Epidemiol 1998; 147:1071.

referencesuptodate· REFERENCES· item f37_62_38890

Shamim T, Golden NH, Arden M, et al. Resolution of vital sign instability: an objective measure of medical stability in anorexia nervosa. J Adolesc Health 2003; 32:73. Katz MG, Vollenhoven B. The reproductive endocrine consequences of anorexia nervosa. BJOG 2000; 107:707. Waller K, Swan SH, Windham GC, et al. Use of urine biomarkers to evaluate menstrual function in healthy premenopausal women. Am J Epidemiol 1998; 147:1071. Doufas AG, Mastorakos G. The hypothalamic-pituitary-thyroid axis and the female reproductive system. Ann N Y Acad Sci 2000; 900:65. Vyver E, Steinegger C, Katzman DK. Eating disorders and menstrual dysfunction in adolescents. Ann N Y Acad Sci 2008; 1135:253. Dalle Grave R, Calugi S, Marchesini G. Is amenorrhea a clinically useful criterion for the diagnosis of anorexia nervosa? Behav Res Ther 2008; 46:1290. Golden NH, Carlson JL. The pathophysiology of amenorrhea in the adolescent. Ann N Y Acad Sci 2008; 1135:163. Golden NH, Jacobson MS, Schebendach J, et al. Resumption of menses in anorexia nervosa. Arch Pediatr Adolesc Med 1997; 151:16. Golden NH, Jacobson MS, Sterling WM, Hertz S. Treatment goal weight in adolescents with anorexia nervosa: use of BMI percentiles. Int J Eat Disord 2008; 41:301. Swenne I. Weight requirements for return of menstruations in teenage girls with eating disorders, weight loss and secondary amenorrhoea. Acta Paediatr 2004; 93:1449. Poyastro Pinheiro A, Thornton LM, Plotonicov KH, et al. Patterns of menstrual disturbance in eating disorders. Int J Eat Disord 2007; 40:424. Bulik CM, Hoffman ER, Von Holle A, et al. Unplanned pregnancy in women with anorexia nervosa. Obstet Gynecol 2010; 116:1136. Koubaa S, Kouba S, Hällström T, et al. Pregnancy and neonatal outcomes in women with eating disorders. Obstet Gynecol 2005; 105:255. Bulik CM, Sullivan PF, Fear JL, et al. Fertility and reproduction in women with anorexia nervosa: a controlled study. J Clin Psychiatry 1999; 60:130. Stewart DE, Robinson E, Goldbloom DS, Wright C. Infertility and eating disorders. Am J Obstet Gynecol 1990; 163:1196. Lo Sauro C, Ravaldi C, Cabras PL, et al. Stress, hypothalamic-pituitary-adrenal axis and eating disorders. Neuropsychobiology 2008; 57:95. Fazeli PK, Lawson EA, Prabhakaran R, et al. Effects of recombinant human growth hormone in anorexia nervosa: a randomized, placebo-controlled study. J Clin Endocrinol Metab 2010; 95:4889.

referencesuptodate· REFERENCES· item f37_62_38890

Lo Sauro C, Ravaldi C, Cabras PL, et al. Stress, hypothalamic-pituitary-adrenal axis and eating disorders. Neuropsychobiology 2008; 57:95. Fazeli PK, Lawson EA, Prabhakaran R, et al. Effects of recombinant human growth hormone in anorexia nervosa: a randomized, placebo-controlled study. J Clin Endocrinol Metab 2010; 95:4889. Mastorakos G, Pavlatou MG, Mizamtsidi M. The hypothalamic-pituitary-adrenal and the hypothalamic- pituitary-gonadal axes interplay. Pediatr Endocrinol Rev 2006; 3 Suppl 1:172. Estour B, Germain N, Diconne E, et al. Hormonal profile heterogeneity and short-term physical risk in restrictive anorexia nervosa. J Clin Endocrinol Metab 2010; 95:2203. Miller KK, Wexler TL, Zha AM, et al. Androgen deficiency: association with increased anxiety and depression symptom severity in anorexia nervosa. J Clin Psychiatry 2007; 68:959. Mehler, PS, Eckel, R, Donahoo, WT. Leptin levels in anorexia nervosa. Int J Eat Disord 1990; 150:894. Misra M, Miller KK, Almazan C, et al. Hormonal and body composition predictors of soluble leptin receptor, leptin, and free leptin index in adolescent girls with anorexia nervosa and controls and relation to insulin sensitivity. J Clin Endocrinol Metab 2004; 89:3486. Misra M, Miller KK, Almazan C, et al. Alterations in cortisol secretory dynamics in adolescent girls with anorexia nervosa and effects on bone metabolism. J Clin Endocrinol Metab 2004; 89:4972. Miller KK, Lawson EA, Mathur V, et al. Androgens in women with anorexia nervosa and normal-weight women with hypothalamic amenorrhea. J Clin Endocrinol Metab 2007; 92:1334. Miller KK, Grieco KA, Klibanski A. Testosterone administration in women with anorexia nervosa. J Clin Endocrinol Metab 2005; 90:1428. Golden NH, Kreitzer P, Jacobson MS, et al. Disturbances in growth hormone secretion and action in adolescents with anorexia nervosa. J Pediatr 1994; 125:655. Grinspoon S, Baum H, Lee K, et al. Effects of short-term recombinant human insulin-like growth factor I administration on bone turnover in osteopenic women with anorexia nervosa. J Clin Endocrinol Metab 1996; 81:3864. Díaz M, Becker DE. Thermoregulation: physiological and clinical considerations during sedation and general anesthesia. Anesth Prog 2010; 57:25. Grinspoon S, Thomas E, Pitts S, et al. Prevalence and predictive factors for regional osteopenia in women with anorexia nervosa. Ann Intern Med 2000; 133:790.

referencesuptodate· REFERENCES· item f37_62_38890

Grinspoon S, Baum H, Lee K, et al. Effects of short-term recombinant human insulin-like growth factor I administration on bone turnover in osteopenic women with anorexia nervosa. J Clin Endocrinol Metab 1996; 81:3864. Díaz M, Becker DE. Thermoregulation: physiological and clinical considerations during sedation and general anesthesia. Anesth Prog 2010; 57:25. Grinspoon S, Thomas E, Pitts S, et al. Prevalence and predictive factors for regional osteopenia in women with anorexia nervosa. Ann Intern Med 2000; 133:790. Winston AP, Alwazeer AE, Bankart MJ. Screening for osteoporosis in anorexia nervosa: prevalence and predictors of reduced bone mineral density. Int J Eat Disord 2008; 41:284. Lucas AR, Melton LJ 3rd, Crowson CS, O'Fallon WM. Long-term fracture risk among women with anorexia nervosa: a population-based cohort study. Mayo Clin Proc 1999; 74:972. Rigotti NA, Neer RM, Skates SJ, et al. The clinical course of osteoporosis in anorexia nervosa. A longitudinal study of cortical bone mass. JAMA 1991; 265:1133. Audí L, Vargas DM, Gussinyé M, et al. Clinical and biochemical determinants of bone metabolism and bone mass in adolescent female patients with anorexia nervosa. Pediatr Res 2002; 51:497. Mehler PS, MacKenzie TD. Treatment of osteopenia and osteoporosis in anorexia nervosa: a systematic review of the literature. Int J Eat Disord 2009; 42:195. Wong S, Au B, Lau E, et al. Osteoporosis in Chinese patients with anorexia nervosa. Int J Eat Disord 2004; 36:104. Baker D, Roberts R, Towell T. Factors predictive of bone mineral density in eating-disordered women: a longitudinal study. Int J Eat Disord 2000; 27:29. Stoffman N, Schwartz B, Austin SB, et al. Influence of bone density results on adolescents with anorexia nervosa. Int J Eat Disord 2005; 37:250. Miller KK, Lee EE, Lawson EA, et al. Determinants of skeletal loss and recovery in anorexia nervosa. J Clin Endocrinol Metab 2006; 91:2931. Bolton JG, Patel S, Lacey JH, White S. A prospective study of changes in bone turnover and bone density associated with regaining weight in women with anorexia nervosa. Osteoporos Int 2005; 16:1955. Bass SL, Saxon L, Corral AM, et al. Near normalisation of lumbar spine bone density in young women with osteopenia recovered from adolescent onset anorexia nervosa: a longitudinal study. J Pediatr Endocrinol Metab 2005; 18:897.

referencesuptodate· REFERENCES· item f37_62_38890

Bolton JG, Patel S, Lacey JH, White S. A prospective study of changes in bone turnover and bone density associated with regaining weight in women with anorexia nervosa. Osteoporos Int 2005; 16:1955. Bass SL, Saxon L, Corral AM, et al. Near normalisation of lumbar spine bone density in young women with osteopenia recovered from adolescent onset anorexia nervosa: a longitudinal study. J Pediatr Endocrinol Metab 2005; 18:897. Klibanski A, Biller BM, Schoenfeld DA, et al. The effects of estrogen administration on trabecular bone loss in young women with anorexia nervosa. J Clin Endocrinol Metab 1995; 80:898. Golden NH, Lanzkowsky L, Schebendach J, et al. The effect of estrogen-progestin treatment on bone mineral density in anorexia nervosa. J Pediatr Adolesc Gynecol 2002; 15:135. Wentz E, Mellström D, Gillberg C, et al. Bone density 11 years after anorexia nervosa onset in a controlled study of 39 cases. Int J Eat Disord 2003; 34:314. Ward A, Brown N, Treasure J. Persistent osteopenia after recovery from anorexia nervosa. Int J Eat Disord 1997; 22:71. Robinson E, Bachrach LK, Katzman DK. Use of hormone replacement therapy to reduce the risk of osteopenia in adolescent girls with anorexia nervosa. J Adolesc Health 2000; 26:343. Strokosch GR, Friedman AJ, Wu SC, Kamin M. Effects of an oral contraceptive (norgestimate/ethinyl estradiol) on bone mineral density in adolescent females with anorexia nervosa: a double-blind, placebo-controlled study. J Adolesc Health 2006; 39:819. Grinspoon S, Herzog D, Klibanski A. Mechanisms and treatment options for bone loss in anorexia nervosa. Psychopharmacol Bull 1997; 33:399. Grinspoon S, Thomas L, Miller K, et al. Effects of recombinant human IGF-I and oral contraceptive administration on bone density in anorexia nervosa. J Clin Endocrinol Metab 2002; 87:2883. Golden NH, Iglesias EA, Jacobson MS, et al. Alendronate for the treatment of osteopenia in anorexia nervosa: a randomized, double-blind, placebo-controlled trial. J Clin Endocrinol Metab 2005; 90:3179. Miller KK, Grieco KA, Mulder J, et al. Effects of risedronate on bone density in anorexia nervosa. J Clin Endocrinol Metab 2004; 89:3903. Golden NH, Katzman DK, Kreipe RE, et al. Eating disorders in adolescents: position paper of the Society for Adolescent Medicine. J Adolesc Health 2003; 33:496.

referencesuptodate· REFERENCES· item f37_62_38890

Golden NH, Iglesias EA, Jacobson MS, et al. Alendronate for the treatment of osteopenia in anorexia nervosa: a randomized, double-blind, placebo-controlled trial. J Clin Endocrinol Metab 2005; 90:3179. Miller KK, Grieco KA, Mulder J, et al. Effects of risedronate on bone density in anorexia nervosa. J Clin Endocrinol Metab 2004; 89:3903. Golden NH, Katzman DK, Kreipe RE, et al. Eating disorders in adolescents: position paper of the Society for Adolescent Medicine. J Adolesc Health 2003; 33:496. Baker SS, Cochran WJ, Flores CA, et al. American Academy of Pediatrics. Committee on Nutrition. Calcium requirements of infants, children, and adolescents. Pediatrics 1999; 104:1152. Holick MF. Vitamin D deficiency. N Engl J Med 2007; 357:266. Gordon CM, Goodman E, Emans SJ, et al. Physiologic regulators of bone turnover in young women with anorexia nervosa. J Pediatr 2002; 141:64. Zunker C, Mitchell JE, Wonderlich SA. Exercise interventions for women with anorexia nervosa: A review of the literature. Int J Eat Disord 2010. Utiger RD. Altered thyroid function in nonthyroidal illness and surgery. To treat or not to treat? N Engl J Med 1995; 333:1562. Rich LM, Caine MR, Findling JW, Shaker JL. Hypoglycemic coma in anorexia nervosa. Case report and review of the literature. Arch Intern Med 1990; 150:894. Zipfel S, Sammet I, Rapps N, et al. Gastrointestinal disturbances in eating disorders: clinical and neurobiological aspects. Auton Neurosci 2006; 129:99. Morris LG, Stephenson KE, Herring S, Marti JL. Recurrent acute pancreatitis in anorexia and bulimia. JOP 2004; 5:231. Mehler PS, Weiner KL. Use of total parenteral nutrition in the refeeding of selected patients with severe anorexia nervosa. Int J Eat Disord 2007; 40:285. Kamal N, Chami T, Andersen A, et al. Delayed gastrointestinal transit times in anorexia nervosa and bulimia nervosa. Gastroenterology 1991; 101:1320. Benini L, Todesco T, Dalle Grave R, et al. Gastric emptying in patients with restricting and binge/purging subtypes of anorexia nervosa. Am J Gastroenterol 2004; 99:1448. Narayanan V, Gaudiani JL, Harris RH, Mehler PS. Liver function test abnormalities in anorexia nervosa--cause or effect. Int J Eat Disord 2010; 43:378. De Caprio C, Alfano A, Senatore I, et al. Severe acute liver damage in anorexia nervosa: two case reports. Nutrition 2006; 22:572.

referencesuptodate· REFERENCES· item f37_62_38890

Benini L, Todesco T, Dalle Grave R, et al. Gastric emptying in patients with restricting and binge/purging subtypes of anorexia nervosa. Am J Gastroenterol 2004; 99:1448. Narayanan V, Gaudiani JL, Harris RH, Mehler PS. Liver function test abnormalities in anorexia nervosa--cause or effect. Int J Eat Disord 2010; 43:378. De Caprio C, Alfano A, Senatore I, et al. Severe acute liver damage in anorexia nervosa: two case reports. Nutrition 2006; 22:572. Boag F, Weerakoon J, Ginsburg J, et al. Diminished creatinine clearance in anorexia nervosa: reversal with weight gain. J Clin Pathol 1985; 38:60. Lowinger K, Griffiths RA, Beumont PJ, et al. Fluid restriction in anorexia nervosa: a neglected symptom or new phenomenon? Int J Eat Disord 1999; 26:392. Brown NW. Medical consequences of eating disorders. South Med J 1985; 78:403. Birmingham CL, Tan AO. Respiratory muscle weakness and anorexia nervosa. Int J Eat Disord 2003; 33:230. Gardini Gardenghi G, Boni E, Todisco P, et al. Respiratory function in patients with stable anorexia nervosa. Chest 2009; 136:1356. Biffl WL, Narayanan V, Gaudiani JL, Mehler PS. The management of pneumothorax in patients with anorexia nervosa: A case report and review of the literature. Patient Saf Surg 2010; 4:1. Filosso PL, Garabello D, Lyberis P, et al. Spontaneous pneumomediastinum: a rare complication of anorexia nervosa. J Thorac Cardiovasc Surg 2010; 139:e79. Hochlehnert A, Löwe B, Bludau HB, et al. Spontaneous pneumomediastinum in anorexia nervosa: a case report and review of the literature on pneumomediastinum and pneumothorax. Eur Eat Disord Rev 2010; 18:107. Hütter G, Ganepola S, Hofmann WK. The hematology of anorexia nervosa. Int J Eat Disord 2009; 42:293. Misra M, Aggarwal A, Miller KK, et al. Effects of anorexia nervosa on clinical, hematologic, biochemical, and bone density parameters in community-dwelling adolescent girls. Pediatrics 2004; 114:1574. Saito S, Kita K, Morioka CY, Watanabe A. Rapid recovery from anorexia nervosa after a life-threatening episode with severe thrombocytopenia: report of three cases. Int J Eat Disord 1999; 25:113. Abella E, Feliu E, Granada I, et al. Bone marrow changes in anorexia nervosa are correlated with the amount of weight loss and not with other clinical findings. Am J Clin Pathol 2002; 118:582.

referencesuptodate· REFERENCES· item f37_62_38890

Saito S, Kita K, Morioka CY, Watanabe A. Rapid recovery from anorexia nervosa after a life-threatening episode with severe thrombocytopenia: report of three cases. Int J Eat Disord 1999; 25:113. Abella E, Feliu E, Granada I, et al. Bone marrow changes in anorexia nervosa are correlated with the amount of weight loss and not with other clinical findings. Am J Clin Pathol 2002; 118:582. Brown RF, Bartrop R, Beumont P, Birmingham CL. Bacterial infections in anorexia nervosa: delayed recognition increases complications. Int J Eat Disord 2005; 37:261. Strumia R. Skin signs in anorexia nervosa. Dermatoendocrinol 2009; 1:268. Castro-Fornieles J, Bargalló N, Lázaro L, et al. A cross-sectional and follow-up voxel-based morphometric MRI study in adolescent anorexia nervosa. J Psychiatr Res 2009; 43:331. Ehrlich S, Burghardt R, Weiss D, et al. Glial and neuronal damage markers in patients with anorexia nervosa. J Neural Transm 2008; 115:921. Roberto CA, Mayer LE, Brickman AM. Brain tissue volume changes following weight gain in adults with anorexia nervosa. Int J Eat Disord 2010. Connan F, Murphy F, Connor SE, et al. Hippocampal volume and cognitive function in anorexia nervosa. Psychiatry Res 2006; 146:117. Strumia R. Dermatologic signs in patients with eating disorders. Am J Clin Dermatol 2005; 6:165. Tyler I, Wiseman MC, Crawford RI, Birmingham CL. Cutaneous manifestations of eating disorders. J Cutan Med Surg 2002; 6:345. Glorio R, Allevato M, De Pablo A, et al. Prevalence of cutaneous manifestations in 200 patients with eating disorders. Int J Dermatol 2000; 39:348. Topic 14705 Version 8.0 © 2013 UpToDate, Inc. All rights reserved. | Subscription and License Agreement | Release: 21.4 - C21.36 Licensed to: Southeast Alabama Med Ctr | Support Tag: [0503-200.131.240.2-C9BE2142DC-S244013.14]