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Walk the Even Hospital Database by book and chapter — the raw source passages that ground Ask, DDx, and the rest.
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©2013 UpToDate ® Print Email Pooled results of randomized controlled trials of antiarrhythmic drugs for maintenance of sinus rhythm after conversion of atrial fibrillation Drug Odds ratio versus control (95% CI, number of trials) Trials reporting side effect Sustained ventricular, arrhythmia, percent Cessation or decreased dose, percent Amiodarone 6.8 (4.0 to 11.4, 2 trials) 0 0 to 9 Propafenone 3.0 (2.0 to 4, 7, 4 trials) 0 to 3 3 to 25 Disopyramide 2.9 (1.4 to 6.1, 2 trials) 0 0 to 55 Sotalol 2.5 (1.7 to 3.7, 4 trials) 0 to 5 5 to 13 Flecainide 4.3 (1.3 to 14.1, 3 trials) 0 0 to 20 percent Quinidine 2.7 (1.1 to 6.8, 4 trials) 0 to 12 4 to 58 Azimilide 1.6 (1.2 to 2.2, 1 trial) 1 5 NOTE: The data in this table cannot be directly applied to clinical practice since the choice of drug will vary with a number of factors including the presence or absence of coronary disease or heart failure. Adapted from McNamara RL, Tamariz LJ, Segal JB, Bass EB. Ann Intern Med 2004; 139:1018.