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OR Clindamycin 600 mg IM or IV 20 mg/kg IM or IV IM: intramuscular; IV: intravenous. * The maximal dose in children should not exceed the dose recommended for adults. • Cephalosporins should not be used in an individual with a history of anaphylaxis, angioedema, or urticaria with penicillins. Δ Or other first- or second-generation oral cephalosporin in equivalent adult or pediatric dose. Reproduced with permission from: Wilson W, Taubert KA, Gewitz M, Lockhart PB, et al. Prevention of Infective Endocarditis. Guidelines From the American Heart Association. A Guideline From the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation 2007; 116:1736. Copyright © 2007 Lippincott Williams & Wilkins.