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contentuptodate· Content· item f41_32_42508

©2013 UpToDate ® Print Email Anticholinergic risk scale* 3 points 2 points 1 Point Amitriptyline Amantadine Carbidopa-levodopa Atropine Baclofen Entacapone Benztropine Cetirizine Haloperidol Carisoprodol Cimetidine Methocarbamol Chlorpheniramine Clozapine Metoclopramide Chlorpromazine Cyclobenzaprine Mirtazapine Cyproheptadine Desipramine Paroxetine Dicyclomine Loperamide Pramipexole Diphenhydramine Loratadine Quetiapine Fluphenazine Nortriptyline Ranitidine Hydroxyzine Olanzapine Risperidone Hyoscyamine Prochlorperazine Selegiline Imipramine Pseudoephedrine-triprolidine (combination) Trazodone Meclizine Tolterodine Ziprasidone Oxybutynin Perphenazine Promethazine Thioridazine Thiothixene Tizanidine Trifluoperazine Note: This is not a complete list of all medications that can cause anticholinergic effects. Class IA antiarrhythmics, which are not listed, have significant dose related anticholinergic effects (disopyramide > procainamide and quinidine) according to the US licensed prescribing information. Point values for these medications were not available in the original publication of this scoring tool.  * To calculate the Anticholinergic Risk Scale score for a patient, identify medications the patient is taking and add the total points for each medication. Reproduced with permission from: Rudolph JL, Salow MJ, Angelini MC, McGlinchey RE. The anticholinergic risk scale and anticholinergic adverse effects in older persons. Arch Intern Med 2008; 168:508. Copyright © 2008 American Medical Association. All rights reserved.