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contentuptodate· Content· item f33_7_33911

©2013 UpToDate ® Print Email Antigen uptake in the gut Antigens may be taken up from the gut lumen by three different cell types. A) Soluble antigen can cross the epithelium via transcellular (endocytosis) or paracellular routes. B) Dendritic cells can extend dendrites into the lumen and sample antigen. C) M cells in Peyer's patches take up particulate antigens. Modified with permission from: Chehade, M, Mayer, L. Oral tolerance and its relation to food hypersensitivities. J Allergy Clin Immunol 2005; 115:3. Illustration used with permission of Elsevier Inc. All rights reserved. Copyright © 2005 Elsevier Inc.