Browse the corpus
Walk the Even Hospital Database by book and chapter — the raw source passages that ground Ask, DDx, and the rest.
1 passage
©2013 UpToDate ® Print Email Aphasia syndromes Syndrome Flu Rep Comp Read Write Localization Wernicke-Lichtheim model Broca's - - + + - "Broca's" area- left inferior frontal, often anterior MCA branch occlusion 1 Wernicke's + - - - - "Wernicke's" area- left superior temporal and inferior parietal region, often posterior MCA branch occlusion 8 Anomic + + + ± ± Temporal, parietal, and occipital regions of cortex outside of classical language areas 6 Conduction + - + + ± Superior temporal gyrus, inferior parietal region adjacent to temporal lobe; classically in arcuate fasciculus 5 Transcortical motor - + + + - Left mesial frontal, especially supplementary motor area; anterior cerebral artery occlusion 4 Transcortical sensory + + - - - Left posterior watershed zone between MCA and PCA territories 7 Transcortical mixed - + - - - Anterior and posterior watershed zones, effectively disconnecting perisylvian cortex from other cortical regions 4,7 Global - - - - - Large MCA or left carotid inclusions infarcting a vast region of the left hemisphere 4,5,7 Pure word deafness + + - + + Left or bilateral superior temporal gyrus lesions 10 Pure alexia + + + - + Left occipital lobe with involvement of splenium of corpus callosum 9 Aphemia - + + + + Motor cortex outflow to articulators 2 Pure agraphia + + + + - Left inferior frontal region 3 Language disorders acquired through brain injury. The first eight rows are aphasic syndromes. Numbers in the column labeled 'Wernicke-Lichtheim model' refer to lesion labels on Figure 1. Flu: fluency; Rep: repetition; Comp: comprehension; Read: reading; Write: writing; +: relatively spared; -: impaired; ACA: anterior cerebral artery; MCA: middle cerebral artery; PCA: posterior cerebral artery. Data from: Mendez, MF, Clark, DG. Neuropsychiatric aspects of aphasia and related disorders. In: The American Psychiatric Publishing Textbook of Neuropsychiatry and Behavioral Neurosciences, 5th ed, Yudofsky, SC, Hales, RH (Eds), American Psychiatric Publishing, Washington, DC 2007. p.522.