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©2013 UpToDate ® Print Email Interstitial lung disease PFT: pulmonary function tests; HRCT: high resolution computed tomography; ILD: interstitial lung disease; BAL: bronchoalveolar lavage; UIP: usual interstitial pneumonia; IPF: idiopathic pulmonary fibrosis; NSIP: nonspecific interstitial pneumonia; OP: organizing pneumonia; PLCH: pulmonary Langerhans cell histiocytosis; TBB: transbronchial lung biopsy. * Serology as indicated by clinical findings: rheumatoid factor, anti-cyclic citrulinated peptide, antinuclear antibody, antisynthetase antibodies, creatine kinase, aldolase, Sjögren's antibodies and scleroderma antibodies. Δ Classic HRCT features of UIP: Reticular opacities in basal and peripheral distribution Traction bronchiectasis Honeycombing (clustered airspaces 3 to 10 mm diameter) in subpleural location Ground glass opacities may be present but are less extensive than reticular opacities Adapted from: Raghu G. Am J Respir Crit Care Med 1995; 151:909.