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©2013 UpToDate ® Print Email Appropriate prescribing in the elderly 1. Is there an indication for the drug? 2. Is the medication effective for the condition? 3. Is the dosage correct? 4. Are the directions correct? 5. Are the directions practical? 6. Are there clinically significant drug-drug interactions? 7. Are there clinically significant drug-disease/condition interactions? 8. Is there unnecessary duplication with other drugs? 9. Is the duration of therapy acceptable? 10. Is this drug the least expensive alternative compared with others of equal usefulness? Reproduced from: Hanlon JT, Schmader KE, Samsa GP, et al. A method for assessing drug therapy appropriateness. J Clin Epidemiol 1992; 45:1045. Illustration used with the permission of Elsevier Inc. All rights reserved.