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Age 10-year stroke risk 45 to 59 years ≥4 percent 55 to 59 years ≥3 percent 60 to 69 years ≥9 percent 60 to 69 years ≥8 percent 70 to 79 years ≥12 percent 70 to 79 years ≥11 percent The table above applies to adults who are not taking NSAIDs and who do not have upper GI pain or a history of GI ulcers. NSAID use and history of GI ulcers increase the risk for serious GI bleeding events considerably and should be considered in determining the balance of benefits and harms. NSAID use combined with aspirin use approximately quadruples the risk for serious GI bleeding events compared with the risk with aspirin alone. The rate of serious bleeding in aspirin users is approximately two to three times greater in patients with a history of GI ulcers. Risk assessment

Stroke risk estimation tool: www.westernstroke.org/PersonalStrokeRisk1.xls Relevant recommendations from the USPSTF The USPSTF has made recommendations on screening for abdominal aortic aneurysm, carotid artery stenosis, CHD, high blood pressure, lipid disorders, and peripheral arterial disease. These recommendations are available at www.preventiveservices.ahrq.gov. CHD: coronary heart disease; CVD: cardiovascular disease; GI: gastrointestinal; HDL: high-density lipoprotein; MI: myocardial infarction; NSAID: nonsteroidal antiinflammatory drug; USPSTF: U.S.  Preventive Services Task Force. Reproduced with permission from: U.S. Preventive Services Task Force. Aspirin for the Prevention of Cardiovascular Disease: U.S. Preventive Services Task Force Recommendation Statement. Ann Intern Med 2009; 150:396. Copyright © 2009 American College of Physicians.