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contentuptodate· Content· item f0_3_50

©2013 UpToDate ® Print Email Histologic features of atypical Spitz tumor In this Spitz tumor with atypical features, the lesion is dome-shaped and circumscribed with a symmetric profile. Histology of atypical Spitz tumor Atypical Spitz tumor. There is a lentiginous melanocytic proliferation with increased cytological atypia and pleomorphism. The lesion lacks eosinophilic globules (Kamino bodies). Cytologic features of atypical Spitz tumor Atypical Spitz tumor. There is increased cytologic atypia within the deep dermal component with irregular nesting pattern.